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UnknownPossible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma.
Not available
S-EPMC8269312 | biostudies-literature
ProteomicsCytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA
The cytotoxic mechanisms of thymidylate synthase inhibitors, such as the multitarget antifolate pemetrexed, are not yet fully understood. Emerging evidence indicates that combining pemetrexed with histone deacetylase inhibitors (HDACi) may enhance therapeutic efficacy in non-small cell lung cancer (...
ORGANISM(S): Homo sapiens (Human) 
2024-12-18 | PXD051824 | Pride
Ber Double strand breaks Base excision repair Histone deacetylase Ap Dihydrofolate reductase Dutpase dut Dhfr Apyrimidinic Deoxyuridine triphosphate nucleotide hydrolase Gart Trifunctional purine biosynthetic protein adenosine 3 Hdac Hdaci Dsb 
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