Triosephosphate isomerase

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O00330 (2)
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CHEBI ID

CHEBI:15422 (4)
CHEBI:15846 (4)
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CHEBI:16908 (4)
CHEBI:17794 (4)
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CHEBI:15946 (3)
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CHEBI:15996 (2)
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CHEBI:18357 (2)

IsPrivate

False (4)

Model Flag

Non Kinetic (2)

First Public Date

2025 (1)
2024 (1)

Modelling Approach

Ordinary differential equation model (4)

Study type

Transcription profiling by array (5)
Animal - High-throughput sequencing (1)
RNA-seq of total RNA (1)
RNA-seq of coding RNA (1)

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Lab affiliation

ACI in Gastroenterology (1)
Bijoya Karmakar, Division of Plant Biology, Bose Institute, Kolkata, India. Swati Gupta Bhattacharya, Professor, Division of Plant Biology Bose Institute 93/1 Acharya Prafulla Chandra Road, Kolkata 700009 (1)
College of Animal Science and Technology, Key Laboratory of Animal Nutrition and Feed Science of Jilin Province, Key Laboratory of Animal Production Product Quality and Security Ministry of Education, Jilin Agricultural University, China (1)
Department of Systems Biology (Physiology). University of Alcala. Spain. (1)
Instituto de Acuicultura Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain (1)
Instituto de Acuicultura Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain. (1)
Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, france (1)
Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia (CBB), Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Av. Alberto Lamego, Campos dos Goytacazes, RJ, Brazil. Unidade de Biologia Integrativa, Setor de Genômica e Proteômica, UENF, Campos dos Goytacazes, RJ, Brazil. (1)
Molecular Signaling Laboratory, Dr. Panjwani Center forMolecular Medicine and Drug Research (PCMD), International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan (1)
Ultrasound Department, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine (1)

Tags

xref:PubMed:39352555 (1)
xref:PubMed:39111287 (1)

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Transcriptome-driven constraint-based modelling reveals metabolic targets for ovarian cancer

OV56 ovarian cancer cell line treated with siTPI1 (siRNA targeted against triose phosphate isomerase 1) and the following negative controls: NTsiRNA (non-targeting siRNA), transfection reagent only and untreated. Experiment designed to assess the effect of TPI1 gene knockdown on OV56 gene expression...

ORGANISM(S): Homo sapiens

2026-04-09 | E-MTAB-16770 | biostudies-arrayexpress

Triosephosphate isomerase is a common crystallization contaminant of soluble His-tagged proteins produced in Escherichia coli.

Not available

S-EPMC3660886 | biostudies-literature

Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase.

Not available

S-EPMC10351538 | biostudies-literature

Male mice express spermatogenic cell-specific triosephosphate isomerase isozymes.

Not available

S-EPMC3916887 | biostudies-literature

Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.

Not available

S-EPMC10459230 | biostudies-literature

Triosephosphate-Isomerase Deficiency: Epiphenomenon or Cause of Loin Pain Haematuria Syndrome?

Not available

S-EPMC9710468 | biostudies-literature

Structural insights from a novel invertebrate triosephosphate isomerase from Litopenaeus vannamei.

Not available

S-EPMC5071168 | biostudies-literature

Neuromuscular dysfunction and pathogenesis in triosephosphate isomerase deficiency.

Not available

S-EPMC11316810 | biostudies-literature

With no lysine kinase 1 in hepatic stellate cells promotes mouse and human liver fibrosis through glycolytic triosephosphate isomerase 1

Liver fibrosis and cirrhosis are major global health burdens with limited treatments. Activated hepatic stellate cells (HSCs) drive fibrosis through increased proliferation, migration, collagen deposition and glycolysis. The aim of this study is to elucidate the signaling events that lead to enhance...

ORGANISM(S): Homo sapiens (Human)

2026-08-13 | PXD078687 | Pride

Loop motions of triosephosphate isomerase observed with elastic networks.

Not available

S-EPMC2556966 | biostudies-literature

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