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GenomicsHomo sapiens
RNA-seq of HeLa cells treated with triterpenoids
PRJNA637753 | ENA
TranscriptomicsSynthetic oleanane triterpenoids reduce tumor growth and promote an anti-tumor immune response independent of cancer KEAP1-mutational status
KEAP1 negatively regulates the cytoprotective factor NRF2 and is commonly inactivated in lung cancer cells. Loss of function KEAP1 mutations in cancer cells contribute to NRF2 activation and tumor immune evasion through immunosuppression and drug resistance. Counterintuitively, treatment with synthe...
ORGANISM(S): Mus musculus 
2025-12-01 | GSE308273 | GEO
GenomicsAnti-oncogenic triterpenoids from Ganoderma lucidum activate circNF1-419 to regulate lipid metabolism and promote apoptosis in glioma
Anti-oncogenic triterpenoids from Ganoderma lucidum activate circNF1-419 to regulate lipid metabolism and promote apoptosis in glioma
PRJNA450542 | ENA
GenomicsAnti-oncogenic triterpenoids from Ganoderma lucidum activate circNF1-419 to regulate lipid metabolism and promote apoptosis in glioma
In order to confirm that L3 (G. lucidum triterpenoids fraction) could influence circRNA expression in glioma, U87 and L3-treated U87 cells were sequenced using an Illumina HiSeq 4000 sequencing system. There were 131 circRNAs identified as down-regulated and 131 circRNAs identified as up-regulated a...
ORGANISM(S): Homo sapiens 
2018-04-18 | GSE113244 | GEO
GenomicsSynthetic oleanane triterpenoids reduce tumor growth and promote an anti-tumor immune response independent of cancer KEAP1-mutational status
Synthetic oleanane triterpenoids reduce tumor growth and promote an anti-tumor immune response independent of cancer KEAP1-mutational status
PRJNA1330027 | ENA
MetabolomicsIntegrative analysis of metabolome and transcriptome reveals new insights into formation and regulation of major components of G. leucocontextum and G. lucidum

Ganoderma is a class of medicinal fungi with diverse medicinal effects, of which triterpenoids are one of the main pharmacologically active substances. In this study, sporocarps of two Ganoderma species (G. leucocontextum, a newly discovered species, and G. lucidum, a traditional medicinal specie...

2026-02-08 | MTBLS13871 | MetaboLights
UnknownBiosynthesis and functions of triterpenoids in cereals.
Not available
S-EPMC12126698 | biostudies-literature
Unknown3,4-Secocycloartane Triterpenoids from the Cones of Pseudolarix amabilis.
Not available
S-EPMC7933301 | biostudies-literature
UnknownNonsterol Triterpenoids as Major Constituents of Olea europaea.
Not available
S-EPMC3317172 | biostudies-literature
UnknownFour New Triterpenoids from Callicarpa kwangtungensis.
Not available
S-EPMC6272150 | biostudies-literature
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