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ProteomicsProteomics of NGF-TrkA signaling dynamics in neuroblastoma cells
We used quantitative mass spectrometry-based proteomics to unravel global nerve growth factor (NGF)-induced TrkA signaling dynamics at the interactome, phosphoproteome and proteome level. A tetracycline-inducible system for TrkA expression was generated in the human neuroblastoma cell line, SH-SY5Y....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080834 | MassIVE
ProteomicsCharacterizing protein phosphorylation downstream of the TrkA receptor
Phosphorylation twenty minutes after stimulation of the TrkA receptor was characterized in PC12 (rat) cells. The study was performed using chimeric receptors, where the endodomain of TrkA was fused to the extracellular domain of PDGFR. As PDGFR (and PDGF) are not expressed in these cells, addition ...
2013-07-11 | MSV000078461 | MassIVE
TranscriptomicsTranscription profiling of human CD34 cells isolated from cord blood or peripheral blood transduced with AML1-ETO or empty vector (MIGR1)
Human CD34 cells isolated from cord blood or peripheral blood transduced with AML1-ETO or empty vector (MIGR1).
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-2049 | biostudies-arrayexpress
UnknownCharacterization of TRKA signaling in acute myeloid leukemia.
Not available
S-EPMC6059018 | biostudies-literature
UnknownDeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkA.
Not available
S-EPMC1899982 | biostudies-literature
UnknownProneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation.
Not available
S-EPMC2442317 | biostudies-literature
UnknownStructural characterization of nonactive site, TrkA-selective kinase inhibitors.
Not available
S-EPMC5255611 | biostudies-literature
UnknownThe Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer.
Not available
S-EPMC7564775 | biostudies-literature
UnknownLight-Inducible Activation of TrkA for Probing Chronic Pain in Mice.
Not available
S-EPMC11756861 | biostudies-literature
UnknownTRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.
Not available
S-EPMC6026011 | biostudies-literature
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