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The aim of this project was to detect phosphorylation on the human calcium Channel TRPC6. TRPC6 is mutated in genetic diseases of the podocyte, a postmitotic cell at the epithelial filtration barrier
ORGANISM(S): Homo sapiens (Human) 
2017-08-23 | PXD005482 | Pride
Ventricles of wild type and TRPC6 knockout hearts
Inducing ferroptosis to impede metastasis by inhibiting the calcium channel TRPC6
Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through b-adrenoceptors
The effect of TRPC6 inhibition in Breast cancer stem cell (BCSC) enriched models
To determine the effect of genetic deletion of TRPC6 in the cardiomyocytes, we compared the mRNA expression levels in the ventricle of a wild-type mouse and a TRPC6 genetic deletion mouse.
ORGANISM(S): Mus musculus 
2026-02-04 | GSE288700 | GEO
As TRPC6 channel induces CREB-mediated trancription, Dental pulp cells from TRPC6-mut patient and from 6 controls were analyzed in order to verify if the disruption of TRPC6 leads to transcriptional changes.
ORGANISM(S): Homo sapiens 
2014-10-23 | GSE62620 | GEO
Effect of Trpc1 or Trpc6 knockout on gene expressions in the hearts of endotoxemic mice
TRPC6 (transient receptor potential cation channel 6) contributes to the ability of breast cancer cells to persist after chemotherapy. Here, we investigated a potential function of TRPC6 in enabling breast cancer cells to resist stimuli that induce ferroptosis. A minority population of quiescent cel...
ORGANISM(S): Homo sapiens 
2026-01-12 | GSE296239 | GEO
Baroreflex control of cardiac contraction (positive inotropy) through sympathetic nerve activation is important to maintain cardiocirculatory homeostasis. Transient receptor potential canonical subfamily (TRPC) channels are responsible for alfa1-adrenoceptor (alfa1AR)-stimulated cation entry and the...
ORGANISM(S): Mus musculus 
2022-09-14 | GSE189494 | GEO
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