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TranscriptomicsGene expression profile of TGFβ3 stimulation and TRPV4 activation/inhibition in the TC28a2 human chondrocyte cell line
RNA-seq of TC28a2 cells following TRPV4 activation/inhibition in the presence and absence of prior TGFβ3 stimulation. The experiment was performed to determine the effect of TRPV4 activity on gene expression in the presence and absence of TGFβ stimulation. TGFβ3 was used to stimulate TGFβ signalling...
ORGANISM(S): Homo sapiens 
2022-01-17 | E-MTAB-10279 | biostudies-arrayexpress
ProteomicsHuman TRPV4 LC-MS protein interactor screen
TRPV4 is a cell surface-expressed calcium-permeable cation channel that mediates cell-specific effects on cellular morphology and function. Dominant missense mutations of TRPV4 cause various forms of inherited neuropathy, but the pathogenic mechanisms are unknown. Using an unbiased screen, we sought...
ORGANISM(S): Homo sapiens (Human) 
2021-01-29 | PXD023758 | Pride
Cmt2c Trpv4 Hek-293t 
ProteomicsStructural dynamics of the chicken TRPV4 N-terminal domain
Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large N-terminal IDR of approximately 150 amino acids. With an in...
ORGANISM(S): Escherichia coli Gallus gallus (Chicken) 
2023-10-24 | PXD041067 | Pride
Trpv4 
TranscriptomicsGene expression profile after TRPV4 knockdown in 3T3-F442A adipocytes
Comparing gene expression profile in 3T3-F442A adipocytes with shRNA against TRPV4 or GFP. TRPV4 is an ion channel expressed in adipocytes. Results provided information that how loss-of-function of TRPV4 affects gene expression in adipocytes. 4 samples were analyzed as two groups: shGFP (control) an...
ORGANISM(S): Mus musculus 
2012-10-12 | E-GEOD-40280 | biostudies-arrayexpress
GenomicsColonic TRPV4 overexpression is related to constipation severity
Colonic TRPV4 overexpression is related to constipation severity
PRJNA858553 | ENA
GenomicsNovel Crosstalk Between Mechanosensitive TRPV4 and NF-κB Inhibits Pulmonary Inflammation
Novel Crosstalk Between Mechanosensitive TRPV4 and NF-κB Inhibits Pulmonary Inflammation
PRJNA1255656 | ENA
GenomicsLoss of TRPV4 reduces pancreatic cancer growth and metastasis
Loss of TRPV4 reduces pancreatic cancer growth and metastasis
PRJNA1257406 | ENA
GenomicsRegulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels
Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels
PRJNA1251083 | ENA
TranscriptomicsColonic TRPV4 overexpression is related to constipation severity
Abstract Background Chronic constipation is prevalent and involves both colon sensitivity and various changes in intestinal bacteria, particularly mucosa-associated microflora. Here we examined regulatory mechanisms of TRPV4 expression by co-culturing colon epithelial cell lines with intestinal bact...
ORGANISM(S): Homo sapiens 
2022-07-15 | GSE208164 | GEO
GenomicsLipoxin B4 Mitigates TRPV4-Activated Muller Cell Gliosis During Ocular Hypertension
Lipoxin B4 Mitigates TRPV4-Activated Muller Cell Gliosis During Ocular Hypertension
PRJNA1312104 | ENA
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