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MAK98 trypanosomes cultured for 7 weeks
The nuclear envelope serves as important mRNA surveillance system. In yeast and human, several control systems act in parallel to prevent nuclear export of unprocessed mRNAs. Trypanosomes lack homologues to most of the involved proteins and their nuclear mRNA metabolism is non-conventional exemplifi...
ORGANISM(S): Trypanosoma brucei 
2018-10-26 | PXD010143 | Pride
Structural chromosomal rearrangements mirror the evolutionary differences between African trypanosomes.
We analysed differentiation of the EATRO1125 strain of Trypanosoma brucei brucei, which was first isolated in 1966 from a bushbuck (Tragelaphus scriptus) in Uganda (origin stated (Bouteillea, 1995) without an original reference.
To analyse gene expression, we isolated at least 3 x 10e8 trypanosom...
ORGANISM(S): Trypanosoma brucei 
The host range of African trypanosomes is influenced by innate protective molecules in the blood of primates. A subfraction of human high-density lipoprotein (HDL) containing apolipoprotein A-I, apolipoprotein L-I, and haptoglobin-related protein is toxic to Trypanosoma brucei brucei but not the hum...
ORGANISM(S): Trypanosoma brucei brucei 
Eukaryotic flagella are complex microtubule based organelles and in many organisms there are extra-axonemal structures present, including the outer dense fibres of mammalian sperm and the paraflagellar rod (PFR) of trypanosomes. We have discovered two cytoplasmic proteins in T. brucei that are requi...
ORGANISM(S): Trypanosoma brucei 
2020-05-20 | PXD018331 | Pride
These are the ribosomal subunit fractions from the polysome gradients. investigating effect of heat shock on procyclic-form trypanosomes.
ORGANISM(S): Trypanosoma brucei brucei 
Mass spectrometry data and proteomic results relating to the manuscript: A novel factor integrating transcription and repression of surface antigen genes in African trypanosomes
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2025-06-26 | MSV000098335 | MassIVE
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