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Unknown
(24)
Proteomics
(2)
Transcriptomics
(1)
Models
(1)
Metabolomics
(1)
Organisms
Leishmania donovani
(1)
Alphavirus
(1)
Anemia
(1)
Betaherpesvirinae
(1)
Cowpox virus
(1)
Coxsackievirus
(1)
Cytomegalovirus
(1)
Dengue virus
(1)
EFO:0001352
(1)
Filoviridae
(1)
Hepatitis B virus
(1)
Human alphaherpesvirus 1
(1)
Human betaherpesvirus 5
(1)
Human immunodeficiency virus
(1)
Human immunodeficiency virus 1
(1)
Human immunodeficiency virus 2
(1)
Influenza A virus
(1)
Influenza C virus
(1)
Japanese encephalitis virus group
(1)
Lyssavirus rabies
(1)
Monkeypox virus
(1)
Nostoc sp. PCC 7120 = FACHB-418
(1)
Oropouche virus
(1)
Orthopoxvirus
(1)
Orthopoxvirus vaccinia
(1)
Rattus
(1)
Staphylococcus aureus
(1)
Streptococcus pneumoniae
(1)
Viruses
(1)
West Nile virus
(1)
Repository
biostudies-arrayexpress
(1)
FAIRDOMHub
(1)
MassIVE
(1)
MetaboLights
(1)
pride
(1)
Disease
Trypanosomiasis
(1)
Technology Type
Mass spectrometry assay
(1)
Mass Spectrometry
(1)
Shotgun proteomics
(1)
Instrument Platform
LTQ Orbitrap Elite
(1)
Liquid Chromatography MS - negative
(1)
Liquid Chromatography MS - positive
(1)
Publication Date
2016
(1)
2014
(1)
2024
(1)
2026
(1)
2022
(1)
Metabolite Name
Thr-Tyr-Asp-Arg-Asn
(1)
[(2R,3S,4S,5R)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-[[(E)-2-methylbut-2-enoyl]oxymethyl]-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl (E)-2-methylbut-2-enoate
(1)
[Met5,Lys6] alpha-Neo-Endorphin (1-6)
(1)
Ile-Val-Ile-Phe-Asn
(1)
2,4,5,6(1H,3H)-Pyrimidinetetrone,5-[2-(2-chlorophenyl)hydrazone]
(1)
Bullatalicin
(1)
15-deoxy--12,14-PGJ2-d4
(1)
2-docosanamidoethanesulfonic acid
(1)
2,6,10,14-Tetramethyl-16-(5-methyl-3,6-dioxo-1,4-cyclohexadiene-1-yl)-2-hydroxy-6,10,14-hexadecatriene-3-one
(1)
[(2S)-2-[9-(3,4-dimethyl-5-propylfuran-2-yl)nonanoyloxy]-3-hydroxypropyl] 11-(3,4-dimethyl-5-propylfuran-2-yl)undecanoate
(1)
(2S,3R,4R,4aR,6aR,6bS,8aS,14bR)-2,3-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylate
(1)
[(2S)-2-hexadecanoyloxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxypropyl] (Z)-octadec-9-enoate
(1)
[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 3-(3-methyl-5-pentylfuran-2-yl)propanoate
(1)
(2R,3R,4R,5R)-2-[(9R)-9,13-dihydroxytridecyl]-5-(hydroxymethyl)pyrrolidine-3,4-diol
(1)
N-Arachidonoyl-3-hydroxy-Aminobutyric Acid
(1)
(1S,4aS,10aR)-6-[(4bS,8S,8aR)-8-carboxy-2-hydroxy-4b,8-dimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-3-yl]-7-hydroxy-1,4a-dimethyl-8-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
(1)
NCGC00384622-01_C34H42O14_(1S,2S,4S,5R,6R,7S,9R,12R)-12-Acetoxy-6-(acetoxymethyl)-2-hydroxy-2,10,10-trimethyl-5-[(2-methylbutanoyl)oxy]-11-oxatricyclo[7.2.1.0~1,6~]dodecane-4,7-diyl di(3-furoate)
(1)
(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-butan-2-yl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
(1)
(4'Z,7'Z,10'Z,13'Z,16'Z,19'Z)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, diester with 1,2,3-propanetriol
(1)
3-Oxolanosta-7,24Z-dien-26-oic acid
(1)
[(2R,3R)-5,7-dihydroxy-2-[3,4,6-trihydroxy-5-oxo-8-[(2R,3S)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-1-yl]-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
(1)
(Gal1-4GlcNAc)2-Sp
(1)
Ala-Lys-Gly-Lys-Ser
(1)
DTDP-4-keto-2-deoxy-beta-L-xylose
(1)
Phe-Lys-Leu-Arg
(1)
Lys-Asn-Leu-Tyr-Thr
(1)
Arg-Leu-Arg-Glu-Lys
(1)
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uloseuronic acid
(1)
Hydrogen trioxo[3-(1lambdachromen-1-ylium-2-yl)phenoxy]-lambdasulfanuide
(1)
(9R,10S,12S,13S,14R,16S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-triene-14,18-diol
(1)
Study type
RNA-seq of coding RNA
(1)
Release Date
2016
(4)
2019
(3)
2014
(3)
2023
(2)
2022
(2)
2008
(2)
2024
(1)
2021
(1)
2020
(1)
2017
(1)
2013
(1)
2011
(1)
2009
(1)
2006
(1)
2005
(1)
Lab affiliation
Analytical Biochemistry and Proteomics Unit,IIBCE & Institut Pasteur de Montevideo
(1)
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Trypanosoma brucei Trypanothione synthetase modification by Ebselen
Identification of Ebselen modification sites on T. brucei Trypanothione synthetase
ORGANISM(S):
Trypanosoma brucei
Escherichia coli
2022-04-04
|
PXD027729
|
Pride
Ebselen
Trypanothione synthetase
Cite
Phenotypic analysis of trypanothione synthetase knockdown in the African trypanosome.
Not available
S-EPMC1276942
|
biostudies-literature
Cite
Leishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activities.
Not available
S-EPMC2427367
|
biostudies-literature
Cite
Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase.
Not available
S-EPMC3581523
|
biostudies-literature
Cite
Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids.
Not available
S-EPMC4829233
|
biostudies-literature
Cite
Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.
Not available
S-EPMC2784880
|
biostudies-literature
Cite
Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening.
Not available
S-EPMC8942522
|
biostudies-literature
Cite
Stage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovani.
Not available
S-EPMC4046939
|
biostudies-literature
Cite
Natural compounds from plants controlling leishmanial growth via DNA damage and inhibiting trypanothione reductase and trypanothione synthetase: an in vitro and in silico approach.
Not available
S-EPMC6650509
|
biostudies-literature
Cite
Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi.
Not available
S-EPMC6331241
|
biostudies-literature
Cite
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