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MetabolomicsAltered milk tryptophan and tryptophan metabolites and health of children born to women with HIV (Haiti study assays).

Children born to women with HIV (WWH) suffer increased morbidity and, in low-income settings, have two to three times the mortality of infants born to women without HIV. The basis for this increase remains elusive. In low-income settings, breastfeeding is recommended because health benefits outwe...

2025-08-26 | MTBLS2573 | MetaboLights
MetabolomicsAltered milk tryptophan and tryptophan metabolites and health of children born to women with HIV (ZEBS study milk assays).

Children born to women with HIV (WWH) suffer increased morbidity and, in low-income settings, have two to three times the mortality of infants born to women without HIV. The basis for this increase remains elusive. In low-income settings, breastfeeding is recommended because health benefits outwe...

2025-08-26 | MTBLS2307 | MetaboLights
MetabolomicsElevated brain manganese induces motor disease by upregulating the kynurenine pathway of tryptophan metabolism
Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
MetabolomicsAssociation between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

Chagas disease causes a cardiac illness characterized by immunoinflammatory reactions leading to myocardial fibrosis and remodeling. The development of Chronic Chagas Cardiomyopathy (CCC) in some patients while others remain asymptomatic is not fully understood, but dysregulated inflammatory resp...

2024-01-11 | MTBLS8390 | MetaboLights
ProteomicsOxidative Cyclization Reagents Reveal Tryptophan Cation-pi interactions
Raw data of the project "Oxidative Cyclization Reagents Reveal Tryptophan Cation-pi interactions"
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-01-18 | MSV000093891 | MassIVE
MetabolomicsTryptophan metabolic disorder in gut-brain axis induces anxiety-like behavior via neuronal pyroptosis in mice exposed to radiofrequency radiation

Radiofrequency radiation (RFR) with specific parameters could alter brain function, yet the underlying mechanisms remain unclear. The gut-brain axis is reported to be important in regulating brain function. Therefore, this study used gut microbiota intervention, regulation of tryptophan metabolit...

2025-09-12 | MTBLS12482 | MetaboLights
MetabolomicsTryptophan metabolic disorder in gut-brain axis induces anxiety-like behavior via neuronal pyroptosis in mice exposed to radiofrequency radiation

Radiofrequency radiation (RFR) with specific parameters could alter brain function, yet the underlying mechanisms remain unclear. The gut-brain axis is reported to be important in regulating brain function. Therefore, this study used gut microbiota intervention, regulation of tryptophan metabolit...

2025-09-12 | MTBLS12483 | MetaboLights
MetabolomicsSerum tryptophan metabolomics in CKD
Not available
ORGANISM(S): Mus musculus 
ST001361 | MetabolomicsWorkbench
MetabolomicsTryptophan metabolites in mouse serum
Not available
ORGANISM(S): Mus musculus 
ST002463 | MetabolomicsWorkbench
MetabolomicsMicrobiota network modules-derived tryptophan metabolites improve cognition via microglial AhR/Sirpα signaling

Gut microbiota dysbiosis has emerged as one of the hallmarks of aging, highlighting the need to identify microbial network modules as new biomarkers rooted in microbiota interactions and develop targeted nutritional interventions. The current research, integrating data from Alzheimer's disease (A...

2026-08-08 | MTBLS12508 | MetaboLights
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