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ProteomicsCardiac Myofibrillogenesis is Spatiotemporally Modulated by the Molecular Chaperone UNC45B
Sarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic stem cell (hESC)-derived cardiomyocytes (CMs) to reveal s...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042075 | Pride
Homo sapiens 
TranscriptomicsGATA factors efficiently direct cardiac fate from ESCs
Gata5 efficiently promotes cardiomyocyte fate from murine ESCs.By removing serum from the culture conditions, GATA4 and GATA6 are each also able to efficiently promote cardiogenesis in ESC derivatives, with some distinctions. Thus, GATA factors can function in ESC derivatives upstream of other car...
ORGANISM(S): Mus musculus 
2013-02-02 | E-GEOD-43831 | biostudies-arrayexpress
GenomicsWdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
The embryonic stem (ES) cell transcriptional and epigenetic networks are critical for the maintenance of ES cell self-renewal. However, it remains unclear whether components of these networks functionally interact and if so, what factors mediate such interactions. Here we show that WD-repeat protein...
ORGANISM(S): Mus musculus 
2011-04-08 | E-GEOD-22934 | biostudies-arrayexpress
UnknownTREAT-AIS: A Multicenter National Registry.
Not available
S-EPMC12778707 | biostudies-literature
UnknownDisease burden attributable to intimate partner violence against females and sexual violence against children in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
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S-EPMC12775558 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownIntensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.
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S-EPMC6652154 | biostudies-literature
UnknownClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
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S-EPMC6193486 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
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S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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