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UnknownRNA binding protein IGF2BP1 synergizes with ETV6-RUNX1 to drive oncogenic signaling in B-cell Acute Lymphoblastic Leukemia.
Not available
S-EPMC10478443 | biostudies-literature
Transcriptomics5'-RACE-Seq analysis of Salmonella hilD and leuO promoters' response to adjacent transcription
Gene silencing by nucleoid-associated protein H-NS is sensitive to neighbouring transcription. This effect does not require neighbouring transcription to elongate into the silenced region. Here we measured how activating transcription of a tetRA cassette positioned upstream of either hilD or leuO pr...
ORGANISM(S): Salmonella enterica subsp. enterica 
2024-10-19 | E-MTAB-13482 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of organoids derived from young and old mice livers
We set up liver-derived organoids to study the ageing progenitor population. We detected epigenetic and transcriptional memory in organoids derived from old mice accompanied by alterations in drug and fatty acid metabolism pathways, similar to phenotypes observed in the liver itself.
ORGANISM(S): Mus musculus 
2024-11-30 | E-MTAB-11097 | biostudies-arrayexpress
TranscriptomicsA flexible microfluidic system for single-cell transcriptome profiling elucidates phased transcriptional regulators of cell cycle
Single cell or single nuclei RNA sequencing of mixed HEK 293 and 3T3 populations using the Nadia droplet sequencing platform. Samples cover different numbers of beads from which cDNA libraries were prepared.
ORGANISM(S): mixed sample 
2021-04-10 | E-MTAB-10296 | biostudies-arrayexpress
UnknownCOVID-19 Patient-Reported Symptoms Using FLU-PRO Plus in a Cohort Study: Associations With Infecting Genotype, Vaccine History, and Return to Health.
Not available
S-EPMC9214183 | biostudies-literature
TranscriptomicsMouse embryonic RNA-seq
The study was aimed at interrogating the early stages of blood cell development within the embryo. Blood develops from mesoderm, which is specified at gastrulation. We therefore sorted cells from mouse embryos between E6.5 and E7.75 to capture gastrulation and the emergence of mesoderm, followed b...
ORGANISM(S): Mus Musculus 
2016-07-08 | E-MTAB-4079 | biostudies-arrayexpress
UnknownDecreased Self-reported Physical Fitness Following SARS-CoV-2 Infection and the Impact of Vaccine Boosters in a Cohort Study.
Not available
S-EPMC10733205 | biostudies-literature
TranscriptomicsSingle-cell RNA-sequencing of spinal cord ependymal cells from FOXJ1-EGFP mice
The spinal cord neural stem cell potential is contained within the ependymal cells lining the central canal. Ependymal cells are, however, heterogeneous and we know little about what this reflects. To gain new insights into ependymal cell heterogeneity, we microdissected the ependymal cell layer fro...
ORGANISM(S): Mus musculus 
2022-12-13 | E-MTAB-11563 | biostudies-arrayexpress
TranscriptomicsSingle-cell phenotyping and RNA sequencing reveal novel patterns of gene expression heterogeneity and regulation during growth and stress adaptation in a unicellular eukaryote
Phenotypic cell-to-cell variability is central for microbial populations and contributes to cell function, stress adaptation and drug resistance. Gene-expression heterogeneity underpins this variability, but has been challenging to study genome-wide. Here, we report a novel approach which combines i...
ORGANISM(S): Schizosaccharomyces pombe 
2018-11-14 | E-MTAB-6825 | biostudies-arrayexpress
UnknownThe electroencephalography protocol for the Accelerating Medicines Partnership® Schizophrenia Program: Reliability and stability of measures.
Not available
S-EPMC12144291 | biostudies-literature
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