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Rheb, a ras-like small GTPase conserved from human to yeast, controls Tor kinase and plays a central role in regulation of cell growth depending on extracellular conditions. Fission yeast Rheb regulates amino acid uptake as well as response to nitrogen starvation. In this study we generated two muta...
ORGANISM(S): Schizosaccharomyces pombe 
CD133-positive immature blasts were purified from bone marrow of the patients. Total RNA was extracted by RNeasy mini spin column (Qiagen, Inc). SUBMITTER_CITATION: Yamashita Y, Ohashi J, Hirai Y, Choi YL, Kaneda R, Fujiwara S-i, Arai Y, Akutsu M, Tsutsumi C, Miyazaki Y, Usuki K, Teramura M, Mitani ...
ORGANISM(S): Homo sapiens 
Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation.We performed ChIP-seq analysis to investigate the role of AR and histone modifications.In addition, by siRNA mediated knockdown of AR-associated factors, changes of AR-binding sit...
ORGANISM(S): Homo sapiens 
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