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ProteomicsOptogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan
Despite longstanding scientific interest in the centrality of mitochondria to biological aging, directly controlling mitochondrial function to test causality has eluded researchers. We show that specifically boosting mitochondrial membrane potential through a light-activated proton pump reversed age...
ORGANISM(S): Caenorhabditis elegans 
2022-11-11 | PXD033901 | Pride
C. elegans Aging 
TranscriptomicsTranscriptional profiling of newly generated dentate granule cells using TU-tagging reveals pattern shifts in gene expression during circuit integration
We sequenced total 10 virus infected mouse hippocampus: 3 samples of lentivirus infected, 4 samples of 1st batch retrovirus infected as batch A, and 3 samples as batch B retrovirus infected. Examination of mRNA levels using TU-tagging approach that differ the newborn neurons from mature neurons.
ORGANISM(S): Mus musculus 
2016-10-25 | E-GEOD-76587 | biostudies-arrayexpress
ProteomicsIdentification of a novel xanthan-binding module of a multi-modular Cohnella sp. xanthanase
A new strain of xanthan-degrading bacteria identified as Cohnella sp. has been isolated from a xanthan thickener for food production. The strain was able to utilize xanthan as the only carbon source and reduce the viscosity of the xanthan-containing medium during cultivation. Xanthan hydrolytic acti...
ORGANISM(S): Cohnella sp. 
2024-06-14 | PXD050379 | Pride
Cbm66 Cohnella Xanthan-binding module Xanthanase Xanthan Mobility shift 
ProteomicsA twin xanthan lyase-dependent xanthan degradation system in Paenibacillus taichungensis I5
Xanthan gum, a natural heteropolysaccharide produced by Xanthomonas species, has many biotechnological applications across industries due to its unique rheological properties. Expanding its utility requires specific enzymes capable of targeted xanthan modification or degradation. In this study, a no...
ORGANISM(S): Paenibacillus taichungensis 
2026-02-02 | PXD068698 | Pride
Xanthanase Gene cluster Paenibacillus taichungensis Xanthan gum Xanthan lyase 
ProteomicsComparative proteomics of meat-spoiling bacteria predicts drivers for their coexistence on modified atmosphere packaged meat
Oxygen and carbon dioxide are common protective gases used in modified atmosphere packaging (MAP) of meat. Within the package, they selectively suppress members of the spoilage microbiome, reshaping it to adapted species concomitantly growing upon MAP. Thus, this species must exhibit adaptation mech...
ORGANISM(S): Leuconostoc gelidum subsp. gelidum Carnobacterium maltaromaticum Leuconostoc gelidum subsp. gasicomitatum Carnobacterium divergens Brochothrix thermosphacta 
2020-02-05 | PXD016382 | Pride
Differential proteomics Carnobacterium divergens Leuconostoc gelidum subsp. gelidum Brochothrix thermosphacta Leuconostoc gelidum subsp. gasicomitatum Carnobacterium maltaromaticum Meat-spoiling bacteria 
ProteomicsFaecal Proteases and Immune Signatures Drive Subtype-Specific Enteric Neuronal Activation in IBS
Background: Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in irritable bowel syndrome (IBS), yet their impact on the enteric nervous system (ENS), the principal regulator of gastrointestinal function, remains unknown. We investigated whether ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-10 | PXD071836 | Pride
Protease-activated receptors (pars) Irritable bowel syndrome Serine and cysteine protease activity Faecal supernatant proteomics Luminal–neuronal signalling axis 
ProteomicsPreparation of a high expression yield bacterial cell extract via lysozyme-assisted sonication
One of the central goals for the development of cell-free (CF) gene expression systems is to ensure reproducible expression of proteins at high quality and yield. Over the past decades, starting from crude cell extracts, a variety of successful preparation protocols have been developed and optimized...
ORGANISM(S): Escherichia coli BL21(DE3) 
2021-08-05 | PXD024458 | Pride
Synthetic biology Cell-free protein expression In vitro transcription-translation Phage assembly Bacterial cell extract 
ProteomicsCemR atypical response regulator impacts energy conversion in Campylobacteria
Campylobacter jejuni and Arcobacter butzleri are microaerobic food-borne human gastrointestinal pathogens that mainly cause diarrheal disease. These related species of the Campylobacteria class face variable atmospheric environments during infection and transmission, ranging from nearly anaerobic to...
ORGANISM(S): Aliarcobacter butzleri RM4018 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 Bacteria 
2024-06-14 | PXD048711 | Pride
Metabolism Arcobacter butzleri Abu0127 Cj1608 Campylobacter jejuni Energy conversion Regulation 
UnknownBiochemical Diagnosis of Phaeochromocytoma and Paraganglioma in Children and Adolescents: A Retrospective Cohort Study.
Not available
S-EPMC12583316 | biostudies-literature
ProteomicsExtracellular Vesicles From Xylella fastidiosa Carry sRNAs and Genomic Islands, Suggesting Roles in Recipient Cells
Xylella fastidiosa (Xf) is a Gram-negative bacterial plant pathogen responsible for severe diseases in a variety of economically important crops. A critical aspect of its virulence is the production of extracellular vesicles (EVs). In this study, we discovered that DNA-binding proteins and non-ribos...
ORGANISM(S): Xylella fastidiosa 
2025-05-27 | PXD056167 | Pride
Small non-coding rnas Bacterial extracellular vesicles Horizontal gene transfer Genomic islands 
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