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TranscriptomicsA transcriptome-wide atlas of RNP compositions reveals diverse classes of mRNAs and lncRNAs
Aim: To determine how different classes of transcript (e.g. lncRNAs and mRNAs) are defined in the cell. Approach: We determined the transcriptome-wide targets of key RNA packaging, maturation, export and turnover factors. We used the CRAC technique, whereby RNA:protein interactions are fixed by UV ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-29 | E-GEOD-46742 | biostudies-arrayexpress
TranscriptomicsTranscriptome-wide Analysis of Exosome Targets in the Budding Yeast Saccharomyces cerevisiae
Purpose: The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. We applied an in vivo cross-linking technique coupled with deep sequencing (CRAC) that captures transcriptome-wide interactions between individu...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-25 | E-GEOD-40046 | biostudies-arrayexpress
TranscriptomicsLoss of the yeast SR protein Npl3 alters gene expression due to transcription readthrough
Yeast Npl3 is a highly abundant RNA binding protein, related to metazoan SR proteins, with reported functions including transcription elongation, splicing and RNA 3’ end processing. To identify direct targets and functions for Npl3, we used UV crosslinking and analysis of cDNA (CRAC) to map precise ...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2015-12-02 | E-MTAB-3642 | biostudies-arrayexpress
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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