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GenomicsTUDCA supplementation in MS
Randomized controlled trial of TUDCA supplementation in people with progressive multiple sclerosis
PRJEB76883 | ENA
ProteomicsSEPN1-related myopathy depends on the oxidoreductase ERO1 alpha and is druggable with the chemical chaperone TUDCA
SEPN1-related myopathy depends on the oxidoreductase ERO1 alpha and is druggable with the chemical chaperone TUDCA
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD047157 | Pride
Tudca Multi mini-core disease Er stress Ero1 Sepn1 Core myopathy 
GenomicsTauroursodeoxycholic Acid (TUDCA) Reduces ER Stress and Disease Activity in Ulcerative Colitis
TUDCA Reduces Ulcerative Colitis Severity
PRJEB73884 | ENA
GenomicsTauroursodeoxycholic Acid (TUDCA) Reduces ER Stress and Lessens Disease Activity in Ulcerative Colitis
TUDCA Reduces Ulcerative Colitis Severity
PRJEB73763 | ENA
TranscriptomicsChanges in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice
We examined the effect of oral TUDCA treatment on hepatic steatosis and associated changes in hepatic gene expression in ob/ob mice. We administered TUDCA to ob/ob mice at a dose of 500 mg/kg twice a day by gastric gavage for 3 weeks. Body weight, glucose homeostasis, endoplasmic reticulum (ER) stre...
ORGANISM(S): Mus musculus 
2010-12-31 | E-GEOD-22608 | biostudies-arrayexpress
GenomicsTranscriptome profile of S. cerevisiae treated with tauroursodeoxycholic acid (TUDCA)
Transcriptome profile of S. cerevisiae treated with tauroursodeoxycholic acid (TUDCA)
PRJNA773716 | ENA
UnknownTauroursodeoxycholic Acid (TUDCA)-Lipid Interactions and Antioxidant Properties of TUDCA Studied in Model of Photoreceptor Membranes.
Not available
S-EPMC8146903 | biostudies-literature
ProteomicsLong-Term Benefits of TUDCA Supplement in ARSACS Zebrafish Model
Our work demonstrated an impairment in cognitive, social and emotional behavior in aged sacs knockout zebrafish similar to that observed in human patients. Transcriptomic and proteomic data from the adult brains revealing alterations in several genes related to circadian rhythms and neuroinflammatio...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-09-03 | PXD058522 | Pride
Sacs-ko model Zebrafis Ataxia of charlevoix-saguenay Tauroursodeoxycholic acid 
GenomicsTauroursodeoxycholic Acid (TUDCA) Reduces ER Stress and Lessens Disease Activity in Ulcerative Colitis
Tauroursodeoxycholic Acid (TUDCA) Reduces ER Stress and Lessens Disease Activity in Ulcerative Colitis
PRJNA1108804 | ENA
TranscriptomicsTranscriptome profile of S. cerevisiae treated with tauroursodeoxycholic acid (TUDCA)
Cells respond to endoplasmic reticulum (ER) stress through activation of signaling pathways such as the Unfolded Protein Response (UPR) which improve the ER folding environment capacity upon changes in misfolded protein burden. Small molecules termed chemical chaperones can attenuate the UPR under s...
ORGANISM(S): Saccharomyces cerevisiae 
2024-11-13 | GSE186390 | GEO
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