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ProteomicsHigh-resolution analyses of the secretomes from primary human skeletal muscle cells
Myokines released by skeletal muscle in response to contraction may contribute to the health-promoting effects of exercise. Previous studies with cultured rodent and human myotubes have revealed highly complex patterns of myokine secretion. However, the commonalities and differences in the secretory...
ORGANISM(S): Homo sapiens (Human) 
2025-04-11 | PXD058612 | Pride
Secretomes Myokines Muscle contraction Mass spectrometry Eps Hskmcs 
ProteomicsHigh-resolution analyses of the secretomes from murine C2C12 myotubes
Myokines released by skeletal muscle in response to contraction may contribute to the health-promoting effects of exercise. Previous studies with cultured rodent and human myotubes have revealed highly complex patterns of myokine secretion. However, the commonalities and differences in the secretory...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-11 | PXD059003 | Pride
C2c12 Secretomes Myokines Muscle contraction Mass spectrometry Eps 
ProteomicsTemporal phosphoproteomics reveals circuitry of phased propagation in insulin signaling
Insulin is a pleiotropic hormone that elicits its metabolic and mitogenic actions through numerous rapid and reversible protein phosphorylations. The temporal regulation of insulin’s intracellular signaling cascade is highly complex and insufficiently understood. We conducted a time-resolved analysi...
ORGANISM(S): Homo sapiens (Human) 
2025-02-13 | PXD058852 | Pride
Phosphoproteomics Donor variability Insulin signaling Skeletal muscle Mrna splicing 
ProteomicsTemporal phosphoproteomics reveals circuitry of phased propagation in insulin signaling
Insulin is a pleiotropic hormone that elicits its metabolic and mitogenic actions through numerous rapid and reversible protein phosphorylations. The temporal regulation of insulin’s intracellular signaling cascade is highly complex and insufficiently understood. We conducted a time-resolved analysi...
ORGANISM(S): Homo sapiens (Human) 
2025-02-13 | PXD043599 | Pride
Phosphoproteomics Donor variability Insulin signaling Skeletal muscle Mrna splicing 
ProteomicsTemporal phosphoproteomics reveals circuitry of phased propagation in insulin signaling
Insulin is a pleiotropic hormone that elicits its metabolic and mitogenic actions through numerous rapid and reversible protein phosphorylations. The temporal regulation of insulin’s intracellular signaling cascade is highly complex and insufficiently understood. We conducted a time-resolved analysi...
ORGANISM(S): Homo sapiens (Human) 
2025-02-13 | PXD043425 | Pride
Phosphoproteomics Donor variability Insulin signaling Skeletal muscle Mrna splicing 
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