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ProteomicsRapid Histone Post-Translational Modification Analysis Using Alternative Proteases and Tandem Mass Tags (RIPUP)
Histone post-translational modifications (PTMs) alter chromatin dynamics and contribute to the regulation of gene expression in health and disease. Mass spectrometry-based analysis is the gold-standard for histone PTM analysis, but it remains constrained by inefficient sample preparation workflows r...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2026-06-20 | PXD073683 | Pride
Post-translational modifications Histones Proteases Lc-ms/ms 
ProteomicsA comparison of blood plasma exosome enrichment strategies for proteomic analysis.
Proteomic analysis of exosomes (EXs) poses a significant challenge. A ‘gold-standard’ method for plasma EX enrichment for downstream proteomic analysis is yet to be established. Methods were evaluated for their capacity to successfully isolate and enrich EXs from plasma, minimise the presence of hig...
ORGANISM(S): Bos taurus (Bovine) 
2022-08-12 | PXD032313 | Pride
Exosome  isolation  enrichment  ultracentrifugation  size-exclusion chromatography  ultrafiltration  mass-spectrometry  proteomics  extracellular vesicles 
ProteomicsThe effects of Alcohol Dependence on the CSF Proteome in Mice: Evidence for Blood-Brain Barrier Dysfunction and Neuroinflammation
A DIA analysis of CSF from individual mice undergoing chronic intermittent ethanol via two-bottle choice (non dependent) method versus vapor group and two bottle choice (dependent).
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-11-03 | MSV000099732 | MassIVE
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