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UnknownMutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics.
Not available
S-EPMC7247294 | biostudies-literature
UnknownUreidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant <i>Neisseria gonorrhoeae</i> H041.
Not available
S-EPMC11812267 | biostudies-literature
UnknownEvidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis.
Not available
S-EPMC6439943 | biostudies-literature
UnknownHow do psychedelics impact people with a history of non-affective psychosis? A qualitative study.
Not available
S-EPMC12722819 | biostudies-literature
UnknownDe novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease.
Not available
S-EPMC5663278 | biostudies-literature
GenomicsWhole genome TraDIS-Xpress assay to determine gene roles during growth of E. coli in different concentrations of the beta-lactam antibiotic meropenem
The aim of the experiment was to assay every gene in the E. coli genome to identify those that contribute to increased or decreased susceptibility to the beta-lactam antibiotic meropenem. A library of transposon-insertion mutants was grown overnight in the presence or absence of a range of concentra...
ORGANISM(S): Escherichia coli K-12 
2022-06-09 | E-MTAB-11802 | biostudies-arrayexpress
TranscriptomicsSheep Tissue Atlas
Sheep total RNA was extracted from embryonic and adult tissues. Sequencing libraries were prepared from the RNA using the Illumina TruSeq stranded total RNA with the Ribo Zero gold option for the rRNA removal. The fragmentation in the standard protocol was modified to increase the average insert siz...
ORGANISM(S): Ovis aries 
2014-12-04 | E-MTAB-3838 | biostudies-arrayexpress
ProteomicsIntraductal xenografts reveal LOX inhibitor PXS-5505 as a translatable targeting strategy for lobular carcinoma exploiting a unique vulnerability
Fifteen percent of breast cancers are invasive lobular carcinomas (ILCs), a specific histological subtype. Although ILCs have distinct clinicopathological features and pathognomonic CDH1 loss, no specific therapies exist because ILCs are underrepresented in clinical trials and preclinical models are...
ORGANISM(S): Homo sapiens (Human) 
2026-01-29 | PXD065164 | Pride
Pxs-5505 Lobular carcinoma Lox inhibitor 
TranscriptomicsRegulation of nucleosome landscape and transcription factor binding at enhancers by BRG1
Enhancers of transcription activate transcription via binding of sequence-specific transcription factors to their target sites in chromatin. In this report, we identify GATA1-bound enhancers genome-wide and find a global reorganization of the nucleosomes at these enhancers during differentiation of ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-26501 | biostudies-arrayexpress
UnknownMental Health Professionals' Perspectives on Digital Remote Monitoring in Services for People with Psychosis.
Not available
S-EPMC12809784 | biostudies-literature
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