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GenomicGenetic Epidemiology Network of Arteriopathy (GENOA)

The Genetic Epidemiology Network of Arteriopathy (GENOA) is one of four networks in the NHLBI Family-Blood Pressure Program (FBPP). GENOA's long-term objective is to elucidate the genetics of target organ complications of hypertension, including both atherosclerotic and arteriolosclerotic com...

phs001238 | dbGaP
TranscriptomicsGlobal changes in gene expression during compatible and incompatible interactions of cowpea (Vigna unguiculata L.) with the root parasitic angiosperm Striga gesnerioides
Background. Cowpea, Vigna unguiculata L. Walp., is one of the most important food and forage legumes in the semi-arid tropics. While most cowpea accessions are susceptible to the root parasitic weed Striga gesnerioides, several cultivars have been identified that show race-specific resistance. Cowpe...
ORGANISM(S): Vigna unguiculata 
2012-09-20 | E-GEOD-39348 | biostudies-arrayexpress
TranscriptomicsMecp2: an unexpected regulator of macrophage gene expression and function
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-66502 | biostudies-arrayexpress
UnknownNeutralizing serum IgE upregulates CD88 and CRTH2 expression on basophils in patients with asthma.
Not available
S-EPMC12701675 | biostudies-literature
GenomicsMecp2: an unexpected regulator of macrophage gene expression and function [ChIP-Seq]
Mutations in methyl-CpG-binding protein 2 (MeCP2), a major epigenetic regulator, are the predominant cause of Rett syndrome. We previously found that Mecp2-null microglia are deficient in phagocytic ability, and that engraftment of wild-type monocytes into the brain of Mecp2-deficient mice attenuate...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-66501 | biostudies-arrayexpress
TranscriptomicsMecp2: an unexpected regulator of macrophage gene expression and function [RNA-Seq]
Mutations in methyl-CpG-binding protein 2 (MeCP2), a major epigenetic regulator, are the predominant cause of Rett syndrome, an X-linked neurodevelopmental disorder. We previously found that Mecp2-null microglia are functionally impaired, and that engraftment of wild-type monocytes into the brain of...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-66211 | biostudies-arrayexpress
TranscriptomicsSynthetic lethal screening with small molecule inhibitors provides a pathway to rational combination therapies for melanoma
Recent data demonstrate that extracellular signals are transmitted through a network of proteins rather than hierarchical signaling pathways. This network model suggests why inhibition of a single component of a canonical pathway, even when targeting a mutationally activated driver of cancer, has in...
ORGANISM(S): Homo sapiens 
2012-12-06 | E-GEOD-39192 | biostudies-arrayexpress
UnknownHigh Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults.
Not available
S-EPMC5455698 | biostudies-literature
TranscriptomicsTranscription profiling by array of Pseudomonas aeruginosa and Enterococcus faecium coculture grown in open circuit (control) and closed circuit (current collecting) to observe the difference in extracellular electron transfer (EET) mechanisms.
Coculture Pseudomonas aeruginosa and Enterococcus faecium were grown in open circuit (control) and closed circuit (current collecting) to observe the difference in extracellular electron transfer (EET) mechanisms. mRNA was extracted, amplified and used on Combimatrix custom arrays to obtain an expre...
ORGANISM(S): Pseudomonas aeruginosa 
2010-08-13 | E-MTAB-320 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Clostridium acetobutylicum grown in open circuit (control) and closed circuit (current collecting) to observe the difference in extracellular electron transfer (EET) mechanisms.
Clostridium acetobutylicum was grown in open circuit (control) and closed circuit (current collecting) to observe the difference in extracellular electron transfer (EET) mechanisms. mRNA was extracted, amplified and used on Combimatrix custom arrays to obtain an expression profile. Analysis was perf...
ORGANISM(S): Clostridium acetobutylicum 
2010-07-09 | E-MTAB-267 | biostudies-arrayexpress
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