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MetabolomicsDiagnostic metabolite biomarkers of chronic typhoid carriage
Background: Salmonella Typhi and Salmonella Paratyphi A are the agents of enteric (typhoid) fever; both can establish chronic carriage in the gallbladder. Chronic Salmonella carriers are typically asymptomatic, intermittently shedding bacteria in the feces, and contributing to disease transmission. ...
2018-01-17 | MTBLS579 | MetaboLights
ProteomicsTyphoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever
Salmonella Typhi secretes typhoid toxin that activates cellular DNA damage responses (DDR) during acute typhoid fever. Human infection challenge studies revealed that the toxin suppresses bacteraemia via unknown mechanisms. By applying proteomics to the plasma of bacteraemic participants, we identif...
ORGANISM(S): Homo sapiens (Human) 
2025-10-28 | PXD058381 | Pride
Typhoid fever Salmonella typhi Human infection challenge 
TranscriptomicsHost response transcriptional profiling of typhoid fever infected Nigerian children
We were able to obtain distinct gene expression profile between children with typhoid fever and other bacteremic infections. Peripheral blood of Nigerian children with typhoid fever and other bacteremic infection were obtained in Paxgene tubes. Total RNa were extracted using Paxgene blood RNA kit a...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-28658 | biostudies-arrayexpress
GenomicsMolecular correlates of vaccine-induced protection against typhoid fever
Molecular correlates of vaccine-induced protection against typhoid fever
PRJNA899913 | ENA
TranscriptomicsMolecular correlates of vaccine-induced protection against typhoid fever
Typhoid fever is caused by the Gram-negative bacterium Salmonella enterica serovar Typhi. Bulk RNA-sequencing (RNA-seq) data were generated from blood samples obtained from adult human volunteers enrolled in a vaccine trial involving two vaccines against typhoid fever, a plain polysaccharide vaccine...
ORGANISM(S): Homo sapiens 
2023-07-19 | GSE217667 | GEO
TranscriptomicsHost response transcriptional profiling of typhoid fever infected Nigerian children
We were able to obtain distinct gene expression profile between children with typhoid fever and other bacteremic infections.
ORGANISM(S): Homo sapiens 
2011-11-29 | GSE28658 | GEO
UnknownSocial and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study.
Not available
S-EPMC6226633 | biostudies-literature
TranscriptomicsVietnam Typhoid Study
Patient Selection: Three hospitals were involved in the study: Dong Thap Provincial and An Giang Provincial hospitals, both located in the Mekong Delta Region of Vietnam where most of the Typhoid patients were admitted, and the Hospital for Tropical Diseases, Ho Chi Minh City, where the malarial pat...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-7000 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serotype SL1344 wildtype, pSf-R27sfh and pSf-R27 at stationary and exponential growth phases, to investigate the role of the Sfh protein encoded by transmissible plasmids and involved in human typhoid
The Sfh protein is encoded by self-transmissible plasmids involved in human typhoid and is closely related to the global regulator H-NS. We have found that Sfh provides a stealth function that allows the plasmids to be transmitted to new bacterial hosts with minimal effects on their fitness. Introdu...
ORGANISM(S): Salmonella enterica serotype Typhimurium 
2007-01-15 | E-SGRP-7 | biostudies-arrayexpress
UnknownComparison of Strategies and Incidence Thresholds for Vi Conjugate Vaccines Against Typhoid Fever: A Cost-effectiveness Modeling Study.
Not available
S-EPMC6226717 | biostudies-literature
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