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no omics definedTranscription profiling of camptothecin treatment time series performed on human U87 glioma cells
Time-series analysis of camptothecin effects on U87 glioma cells
ORGANISM(S): Homo sapiens 
2006-09-30 | E-MEXP-741 | biostudies-arrayexpress
TranscriptomicsmiRNA analysis of HBMVECs exposed or unexposed to U87 glioma cells
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here we demonstrate that a small regulatory microRNA, miR-296 has a major role in this process. Glioma cells and angiogenic growth factors elevate the level of miR-296 in primary human brain microvascular...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13091 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression levels in parental U87 cells and U87 tumor spheres treated with or without ITE
The formation of U87 tumor spheres was associated with expression changes of many genes which was reverted by the treatment with ITE(2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester). We used DNA microarrays to profile gene expression in U87 tumor spheres treated with ITE and ident...
ORGANISM(S): Homo sapiens 
2015-04-18 | E-GEOD-67986 | biostudies-arrayexpress
TranscriptomicsExpression data from cells overexpressing c19orf63 (HSS1) [U87]
U87 cell lines were stable transfected with C19ORF63 (Human hematopoietic peptide secreted-1 - HSS1). HSS1 is a truly novel protein defining a new class of secreted factors. U87 cell line overexpressing HSS1 greatly reduced their proliferation rate compared to mock-transfected cells. Microarray ana...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-61779 | biostudies-arrayexpress
TranscriptomicsGene profiling: U87 IRE1 dominant negative cells vs. U87ctrl cells in culture
Transcriptome analysis was performed from human U87 glioblastoma cell clones: U87 IRE1.NCK DN (U87dn, IRE1 dominant negative) and U87 control (U87ctrl, empty plasmid). Cells were grown in DMEM supplemented with 10% FBS and glutamine for 16 hours in culture prior mRNA isolation and analyses U87dn c...
ORGANISM(S): Homo sapiens 
2010-08-08 | E-GEOD-22385 | biostudies-arrayexpress
TranscriptomicsG72 overexpression in U87 cells
G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In some reports, G72 genetic variation also related with bipolar disorder. Although G72 has been studied for 15 years, the protein function is still unc...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-67704 | biostudies-arrayexpress
TranscriptomicsTranscription profiling array of human glioblastoma cell line U87 comparing control cells with U87-shLIN7a knockdown cells and rescue cells which have the same Lin7a knockdown but re-express Lin7a lentivirally (U87-shLin7a+Lin7A)
After performing an in-vivo screening with U87 glioblastoma cells transduced with a knockdown library several genes could be identified. Lin7a which was one of the candidates was further evaluated. Single knockdown of Lin7a in U87 conferred a pro-invasive phenotype in-vitro and in-vivo. Overexpressi...
ORGANISM(S): Homo sapiens 
2017-08-27 | E-MTAB-5871 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of U87 cells after transfection with hsa-miR-145-5p and 31-5p
We analyzed the expression profiles of hsa-miR-145-5p or hsa-miR-31-5p-targeting genes relating to invasion or migration after co-overexpression of hsa-miR-145-5p and 31-5p Gene expression profiles of U87 cells after co-transfection with hsa-miR-145-5p and 31-5p mimics, and U87 cells after transfect...
ORGANISM(S): Homo sapiens 
2016-06-23 | E-GEOD-83643 | biostudies-arrayexpress
TranscriptomicsProfile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes
Purpose: We identified KPC1 as the ubiquitin ligase that binds to the p105 precursor of NF-kB, ubiquitinates it and mediates its proteasomal processing to generate the p50 active subunit of the transcription factor. Using U87-MG human glioblastoma xenografts, we observed that overexpression of KPC1 ...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-60530 | biostudies-arrayexpress
GenomicsHomo sapiens strain:U87
Homo sapiens strain:U87 Transcriptome or Gene expression
PRJNA415572 | ENA
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