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TranscriptomicsMELK and UBE2C gene knockdown in prostate cancer cell line PC3
In order to address the putative role of MELK and UBE2C in prostate cancer development and progression, we performed functional analysis upon siRNA-based knockdown, and searched for downstream genes and processes by microarray experiments. RNAi-based inhibition of MELK and UBE2C was efficient in PC3...
ORGANISM(S): Homo sapiens 
2012-10-19 | E-GEOD-32873 | biostudies-arrayexpress
ProteomicsChanges in proteome upon deletion of UBE2S/UBE2C in HCT116 cells
The proteome of HCT116 cells deleted of UBE2S and/or UBE2C was compared to the proteome of wild-type HCT116 cells.
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD003443 | Pride
Hct116 Ube2s Ube2c 
GenomicsUBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival
UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival
PRJNA833957 | ENA
GenomicsTranscriptomic profiling of UBE2C depletion and overexpression in MCF-7 breast cancer cells
Transcriptomic profiling of UBE2C depletion and overexpression in MCF-7 breast cancer cells
PRJNA1512419 | ENA
TranscriptomicsTranscriptomic profiling of UBE2C depletion and overexpression in MCF-7 breast cancer cells
This study examined transcriptomic changes associated with both UBE2C depletion and UBE2C overexpression in MCF-7 human breast cancer cells. Two independent bulk RNA-sequencing comparisons were included: a CRISPR/Cas9-derived UBE2C-depleted clone and its corresponding sgCtrl clone, and UBE2C-overexp...
ORGANISM(S): Homo sapiens 
2026-08-18 | GSE343698 | GEO
TranscriptomicsUBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival
To gain insight into the pathobiology of hepatoblastoma (HB), RNA sequence analysis and protein-protein interaction analysis of previously established and sequenced HB samples were conducted. Ubiquitination was identified as a key pathway dysregulated in HB and UBE2C, encoding an E2 ubiquitin ligase...
ORGANISM(S): Homo sapiens 
2023-04-30 | GSE201996 | GEO
TranscriptomicsMELK and UBE2C gene knockdown in prostate cancer cell line PC3
In order to address the putative role of MELK and UBE2C in prostate cancer development and progression, we performed functional analysis upon siRNA-based knockdown, and searched for downstream genes and processes by microarray experiments. RNAi-based inhibition of MELK and UBE2C was efficient in PC3...
ORGANISM(S): Homo sapiens 
2012-10-19 | GSE32873 | GEO
UnknownPan-Cancer Bioinformatics Analysis of Gene UBE2C.
Not available
S-EPMC9091452 | biostudies-literature
UnknownDeregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression.
Not available
S-EPMC6002383 | biostudies-literature
UnknownA Comprehensive Bioinformatics Analysis of UBE2C in Cancers.
Not available
S-EPMC6539744 | biostudies-literature
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