Sort   by:  
 Page size 
ProteomicsCryo-EM structure of the human COP1-DET1 ubiquitin ligase complex
Ubiquitin modification regulates fundamental cellular processes by controlling protein stability and function. The ubiquitin ligase COP1, conserved from plants to humans, targets developmental transcription factors. COP1 can act on its own or be incorporated into CULLIN4–RING ligase (CRL4) complexes...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD071633 | Pride
Human Cop1-det1 ubiquitin ligase Cx-ms 
UnknownNoncoding variation near UBE2E2 orchestrates cardiometabolic pathophenotypes through polygenic effectors.
Not available
S-EPMC11790016 | biostudies-literature
UnknownUBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Not available
S-EPMC9918489 | biostudies-literature
UnknownType 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.
Not available
S-EPMC4902507 | biostudies-literature
UnknownPPARG, TMEM163, UBE2E2, and WFS1 Gene Polymorphisms Are Not Significant Risk Factors for Gestational Diabetes in the Polish Population.
Not available
S-EPMC8878167 | biostudies-literature
UnknownImpact of KCNQ1, CDKN2A/2B, CDKAL1, HHEX, MTNR1B, SLC30A8, TCF7L2, and UBE2E2 on risk of developing type 2 diabetes in Thai population.
Not available
S-EPMC5989367 | biostudies-literature
TranscriptomicsRNA-seq analysis to examine the effect of the Ube2e1 and Ube2e1 knockdown on gene expression profile in 3T3-L1 pre-adipocyte cells
UBE2E2 and UBE2E1 are both members of the same family of E2 conjugating enzymes raising the question of whether they are functionally redundant, particularly given that genetic targeting of both genes inhibited adipogenesis, in vitro. To explore this question, we sought to test for molecular redunda...
ORGANISM(S): Mus musculus 
2025-01-09 | GSE268800 | GEO
GenomicsChromatin accessibility analysis of human mesenchymal stem cells
We integrated ATAC-seq analyses of human MSC with CRISPRi screening to identify potential regulatory regions controlling UBE2E2 expression and/or UBE2E1 expression.
ORGANISM(S): Homo sapiens 
2025-01-09 | GSE269375 | GEO
UnknownMultiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.
Not available
S-EPMC5451114 | biostudies-literature
UnknownCryo-EM structure of the human COP1-DET1 ubiquitin ligase complex.
Not available
S-EPMC12808801 | biostudies-literature
Sort   by:  
 Page size