Covalent modifications of proteins with ubiquitin and ubiquitin-like molecules are instrumental to most, if not all biological processes. However, identifying the E3 ligase responsible for these modifications remains a major bottleneck in ubiquitin research. Here, we have developed an E2-thioester-d...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast)