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TranscriptomicsInterferon Regulatory Factor 4 Modulates Epigenetic Silencing and Cancer-Critical Pathways in Melanoma Cells
Interferon Regulatory Factor 4 (IRF4) is a transcription factor initially identified as a key controller in lymphocyte differentiation and function, and subsequently as a dependency factor and therapy target in lymphocyte-derived cancers. In melanocytes, IRF4 takes part in the regulation of pigmenta...
ORGANISM(S): Homo sapiens 
2024-07-01 | GSE244460 | GEO
ProteomicsIdentification of ubiquitination targets of UHRF1
The reversible attachment of ubiquitin governs the interaction, activity and degradation of proteins whereby the type and target of this conjugation determine the biological response. The investigation of this complex and multi-faceted protein ubiquitination mostly relies on painstaking biochemical ...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-30 | PXD034335 | Pride
Posttranslational modifications (pmt) Ubiquitination Protein degradation Dna methylation Heterochromatin binding protein (hp1) Uhfr1 
GenomicsInterferon Regulatory Factor 4 Modulates Epigenetic Silencing and Cancer-Critical Pathways in Melanoma Cells
Interferon Regulatory Factor 4 Modulates Epigenetic Silencing and Cancer-Critical Pathways in Melanoma Cells
PRJNA1023214 | ENA
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