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ProteomicsHSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B cell receptor signaling
Burkitt’s lymphoma (BL) is an aggressive B-cell neoplasm that is currently treated by intensive chemotherapy in combination with anti-CD20 antibodies. Because of their toxicity, current treatment regimens are often not suitable for elderly patients or for patients in developing countries where BL is...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080781 | MassIVE
TranscriptomicsRNA-seq of murine spleen B-cells after pentanoate treatment compared to untreated control
We tested the influence of pentanoate on B cells by treatment of CpG-stimulated B cells in vitro. We isolated naive B cells from FIR/TIGER mice (IL-10 (GFP) - Foxp3 (RFP) - Reporter mice) from spleen. Cells were cultured in presence of 5 µg/ml CpG 2395. 24h after CpG-stimulation, B cells were treate...
ORGANISM(S): Mus musculus 
2019-01-15 | E-MTAB-6115 | biostudies-arrayexpress
OtherLysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.
Data from ProteomeXchange: PXD ID: PXD001114. Experiment: LysargiNase, silac, file: LR_Ulilysin_PMA_A1_121126.mzml. Published as part of . From the Abstract: {{i}} To improve proteome coverage and protein C-terminal identification, we characterized the Methanosarcina acetivorans thermophilic protei...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005457 | GPMDB
Resource Reanalysis 
TranscriptomicsCD3+ T-cells of B-cell chronic lymphocytic leukemia
Analysis of T-cells isolated from CD3+ T-cells of patients with B-cell chronic lymphocytic leukemia (B-CLL). In contrast to other types of cancers, the non-malignant T-cell compartment of B CLL patients is expanded. Results provide insights into the role of T-cells in B-CLL. Purified T-cells of B-CL...
ORGANISM(S): Homo sapiens 
2009-11-25 | E-GEOD-19147 | biostudies-arrayexpress
UnknownCVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Not available
S-EPMC8245475 | biostudies-literature
TranscriptomicsBL2 cells stimulated with B cell specific paracrine stimuli
Expression data of BL2 Burkitt Lymphoma cell line (controls and samples treated with different B cell specific stimuli) BL2 cells were cultured in RPMI and stimulated with the respective agents (rhCD40L, rhIL21, rhBAFF, LPS and antiIgM F(ab) fragments) for indicated timepoints. Cells were harvested ...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-42660 | biostudies-arrayexpress
UnknownHighly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses.
Not available
S-EPMC6708359 | biostudies-literature
UnknownCirculating B-vitamin biomarkers and B-vitamin supplement use in relation to quality of life in patients with colorectal cancer: results from the FOCUS consortium.
Not available
S-EPMC8168355 | biostudies-literature
UnknownP2X7 receptor isoform B is a key drug resistance mediator for neuroblastoma.
Not available
S-EPMC9458077 | biostudies-literature
UnknownInduction of p21CIP1 protein and cell cycle arrest after inhibition of Aurora B kinase is attributed to aneuploidy and reactive oxygen species.
Not available
S-EPMC4047381 | biostudies-literature
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