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GenomicsENVISION I ADD I 3.0 um prokaryotes
ENVISION I Microcosm ADD I 3.0 um prokaryotes
PRJEB42359 | ENA
TranscriptomicsMF59 and Pam3CSK4 boost adaptive responses to influenza subunit vaccine through an IFN type I independent mechanism of action
Analysis of whole mouse muscle and inguinal lymph node gene expression signature induced after 6h by in-vivo intramuscularly administration of MF59, alum, CpG, resiquimod (R848), Pam3CSK4 and DMSO and PBS controls. Analysis of splenocyte gene expression signature induced by the same treatments after...
ORGANISM(S): Mus musculus 
2012-02-22 | E-MTAB-942 | biostudies-arrayexpress
GenomicsENVISION I ADD I 0.22 um prokaryotes
ENVISION I Microcosm ADD I (0.22 size fraction prokaryotes)
PRJEB36712 | ENA
ProteomicsCryoEM structure of mitochondrial complex I from the thermophilic eukaryote Chaetomium thermophilum
Mitochondrial complex I is a redox-driven proton pump that generates most of the proton-motive force powering oxidative phosphorylation and ATP synthesis in eukaryotes. We report the structure of complex I from the thermophilic eukaryote Chaetomium thermophilum, determined by electron cryo-microscop...
ORGANISM(S): Chaetomium thermophilum 
2022-11-29 | PXD033234 | Pride
Mitochondrial complex i Chaetomium thermophilum 
ProteomicsECM-Focused Proteomic Analysis of Ear Punch Regeneration in Acomys cahirinus
In mammals, significant injury is generally followed by the formation of a fibrotic scar which provides structural integrity but fails to functionally restore damaged tissue. Spiny mice of the genus Acomys represent the first example of full skin autotomy in mammals. Acomys cahirinus h...
ORGANISM(S): Mus musculus (Mouse) Acomys cahirinus 
2025-10-31 | PXD047626 | Pride
Proteomics Regeneration Tandem mass spectrometry Wound healing Matrisome Scar-free Fibrosis Acomys cahirinus Spiny mouse Extracellular matrix 
TranscriptomicsTranscriptome analysis in macrophages treated with type I interferon, heat-killed Listeria monocytogenes, or both.
To define the group of genes which is synergistically induced by cooperative activity of the type I interferon - activated Jak/STAT pathway and other pathways, we treated bone marrow-derived macrophages (BMDM) with heat-killed Listeria (hkL; non-STAT pathways activated), type I interferon alone (onl...
ORGANISM(S): Mus musculus 
2015-06-15 | E-MTAB-3015 | biostudies-arrayexpress
ProteomicsFully unsupervised identification of HLA-I motifs
The precise identification of Human Leukocyte Antigen class I (HLA-I) binding motifs plays a central role in our ability to understand and predict (neo-)antigen presentation in infectious diseases and cancer. Here, by exploiting co-occurrence of HLA-I alleles across publicly available as well as ten...
ORGANISM(S): Homo sapiens (Human) 
2017-08-18 | PXD005231 | Pride
Hla peptidome Immunopeptidomics Lc-ms/ms 
ProteomicsMHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection
We sought to build a catalog of epitopes presented by breast cancers using a renewable resource of well-characterized breast cancer cell lines. Starting from 70 breast cancer cell lines, we measured MHC class I abundance and used pre-existing RNAseq data to identify either HLA-A*02 or MHC class I-po...
ORGANISM(S): Homo sapiens (Human) 
2018-01-16 | PXD006406 | Pride
Immune system Mass spectrometry Human Mhc class 1 ligands Hla typing Peptide sequencing Breast cancer Cell lines Immunoprecipitation Rna-seq 
TranscriptomicsMicroRNA profiling by array of mouse skeletal muscle cells treated with TNF-alpha or IGF-I
Murine skeletal muscle cells pmi28 were cultured in growth medium (HamM-^Rs F10, supplemented with 20 % FCS, 2 mM L-glutamine, and 1 % Penicillin / Streptomycin). Myoblasts were cultured on laminin-1 coated dishes for an additional 24 h before switching a fraction of dishes to differentiation medium...
ORGANISM(S): Mus musculus 
2013-05-15 | E-MTAB-1114 | biostudies-arrayexpress
TranscriptomicsE-cadherin and EMT regulation by bHLH factors: a new role for the class I gene E2-2 (TCF4) and its comparison with E47.
Loss of expression of the cell-cell adhesion molecule E-cadherin is an essential event for epithelial-mesenchymal transition (EMT), a process that allows cell migration in the developing embryo and during tumour invasion. Transcriptional repression has emerged as the main mechanism responsible for E...
ORGANISM(S): Canis lupus familiaris 
2010-06-24 | E-GEOD-9145 | biostudies-arrayexpress
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