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MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
TranscriptomicsmRNA-Seq expression and MS3 proteomics profiling of human post-mortem BA9 brain tissue for Parkinson Disease and neurologically normal individuals
Parkinson disease (PD) is a neurodegenerative disease characterized by the accumulation of alpha-synuclein (SNCA) and other proteins in aggregates termed “Lewy Bodies” within neurons. PD has both genetic and environmental risk factors, and while processes leading to aberrant protein aggregation ...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-68719 | biostudies-arrayexpress
UnknownExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments.
Not available
S-EPMC6084352 | biostudies-literature
UnknownMRMAssayDB: an integrated resource for validated targeted proteomics assays.
Not available
S-EPMC6184479 | biostudies-literature
ProteomicsPhage Phix174 - Wildtype and engineered proteome
Sequence overlap between two genes is common across all genomes, with viruses having particularly high proportions of these gene overlaps. The natural biological function and effects on fitness of gene overlaps are not fully understood and their effects on gene cluster and genome-level refactoring a...
ORGANISM(S): Escherichia Virus Phix174 Synthetic Enterobacteria Phage Phix174.1f 
2021-06-15 | PXD019681 | panorama
TranscriptomicsEstimating accuracy of absolute gene expression measurement by RNA-Seq and microarrays with proteomics
Microarrays revolutionized biological research by enabling gene expression comparisons on a transcriptome-wide scale. Microarrays, however, do not estimate absolute expression level accurately. At present, high throughput sequencing is emerging as an alternative methodology for transcriptome studies...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-13744 | biostudies-arrayexpress
UnknownExploring the potential of public proteomics data.
Not available
S-EPMC4738454 | biostudies-literature
ProteomicsYPIC challenge 2018: A case study in characterizing an unknown protein sample
For the YPIC challenge 2018 contestants were invited to try to decipher two unknown English questions encoded by a synthetic protein expressed in E. coli. We present how we analyzed this unknown sample using a tryptic digest with dynamic exclusion disabled to increase the signal-to-noise ratio of t...
ORGANISM(S): Escherichia coli 
2019-06-11 | PXD014003 | Pride
Spectral clustering Spectral networking Ypic De novo Synthetic protein 
UnknownMaking proteomics data accessible and reusable: current state of proteomics databases and repositories.
Not available
S-EPMC4409848 | biostudies-literature
UnknownproBAMsuite, a Bioinformatics Framework for Genome-Based Representation and Analysis of Proteomics Data.
Not available
S-EPMC4813696 | biostudies-literature
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