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TranscriptomicsTranscription profiling of human endothelial progenitor cells (EPC) vs. human umbilical vein endothelial cells (HUVEC) vs. CD14+ monocytes
Comparison of mRNA expression in human EPC vs. HUVEC vs. human monocytes. Cell-type specific gene expression under basal cell culture conditions (no stimulation). The hybridization was performed with three samples of EPC vs. three samples of HUVEC vs. 3 samples of CD14+ monocytes. â?¢ The origin of ...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-2040 | biostudies-arrayexpress
TranscriptomicsRNAi of human HUVEC cells knocked down for HDAC isoenzymes reveals sHDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells
Class IIa histone deacetylases (HDACs) are signal-responsive regulators of gene expression involved in vascular homeostasis. To investigate the differential role of class IIa HDACs for the regulation of angiogenesis, we used siRNA to specifically suppress the individual HDAC isoenzymes. Among the HD...
ORGANISM(S): Homo sapiens 
2009-04-11 | E-GEOD-15499 | biostudies-arrayexpress
TranscriptomicsMembers of the microRNA-17-92 cluster exhibit a cell intrinsic anti-angiogenic function in endothelial cells
MicroRNAs are endogenously expressed small non-coding RNAs that regulate gene expression on the posttranscriptional level. The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia. Whereas miR-92a was recently identifi...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20745 | biostudies-arrayexpress
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