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MetabolomicsA statistical analysis of the effects of urease pre-treatment on the measurement of the urinary metabolome by gas chromatography–mass spectrometry
Urease pre-treatment of urine has been utilized since the early 1960s to remove high levels of urea from samples prior to further processing and analysis by gas chromatography–mass spectrometry (GC–MS). Aside from the obvious depletion or elimination of urea, the effect, if any, of urease pre-treatm...
2014-05-21 | MTBLS71 | MetaboLights
MetabolomicsLuteolin as a urease inhibitor: a novel therapeutic strategy against Helicobacter pylori

The rising prevalence of antibiotic-resistant Helicobacter pylori (H. pylori) underscores the urgent need for alternative treatment strategies. By producing ammonia to neutralize gastric acid, the key virulence factor urease is essential for H. pylori&nbs...

2026-02-28 | MTBLS13581 | MetaboLights
MetabolomicsA statistical analysis of the effects of urease pre-treatment on the measurement of the urinary metabolome by gas chromatography–mass spectrometry
Not available
ORGANISM(S): Homo sapiens 
ST000092 | MetabolomicsWorkbench
TranscriptomicsProteus mirabilis UreR Coordinates Cellular Functions required for Urease Activity
Catheter-associated urinary tract infections (CAUTIs) account for over 30% of acute nosocomial infections in the U.S. and generate $340 million in healthcare costs annually. A major causative agent of CAUTIs is Proteus mirabilis, an understudied Gram-negative pathogen noted for its ability to form u...
ORGANISM(S): Proteus mirabilis 
2024-03-25 | GSE254779 | GEO
GenomicsProteus mirabilis UreR Coordinates Cellular Functions required for Urease Activity
Proteus mirabilis UreR Coordinates Cellular Functions required for Urease Activity
PRJNA1071682 | ENA
TranscriptomicsTranscriptomic changes in maize roots triggered by urease inhibitor NBPT
In the soil the stability of urea is affected by the presence of urease, a ubiquitous enzyme released in the rhizosphere by microbial population and by decomposition of organic matter. To reduce the impact on farmer economies and environmental pollution, a common agronomical practice consists of app...
ORGANISM(S): Zea mays 
2017-02-09 | GSE76828 | GEO
GenomicsUrease inhibitors changed soil prokaryotic community structure
Effect of urease inhibitors on urea degradation rate and soil prokaryotic community structure in a short-term experimental incubation
PRJEB26588 | ENA
GenomicsSporosarcina koreensis
Urease-producing bacteria
PRJNA1434713 | ENA
TranscriptomicsThe cockroach Blattella germanica obtains nitrogen from uric acid through a metabolic pathway shared with its bacterial endosymbiont
Uric acid stored in the fat body of cockroaches is a nitrogen reservoir mobilized in times of scarcity. The discovery of urease in Blattabacterium cuenoti, the primary endosymbiont of cockroaches, suggests that the endosymbiont may participate in cockroach nitrogen economy. However, bacterial urease...
ORGANISM(S): Blattella germanica 
2014-12-08 | E-GEOD-63921 | biostudies-arrayexpress
UnknownZerumbone Inhibits Helicobacter pylori Urease Activity.
Not available
S-EPMC8124612 | biostudies-literature
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