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ProteomicsAnalysis of the urine proteome for biomarker discovery.
Characterization of exosome-free urinary proteome from healthy donors using LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046113 | Pride
Urine Proteomics Biomarkers 
UnknownUrinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers.
Not available
S-EPMC11762655 | biostudies-literature
ProteomicsComprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Noninvasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model
To investigate the potential noninvasive early biomarkers of AD in 5XFAD mouse model, we investigate the proteome of urinary exosomes present in 1-month-old (before amyloid-β accumulation) 5XFAD mouse models and their littermate controls. Another two groups of 2 and 6 months-old urinary samples were...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD021935 | Pride
Urinary exosome proteome Alzheimer’s disease 5xfad mouse model Early diagnosis Biomarkers 
UnknownPerturbations in the urinary exosome in transplant rejection.
Not available
S-EPMC4292055 | biostudies-literature
ProteomicsElucidation of urinary extracellular vesicle protein signatures from patients with cribriform and intraductal prostate carcinoma
A comprehensive systemic assessment of the proteome changes that occur in prostate cancer (PCa) during the onset and course of the illness may produce results that are clinically significant. Proteins, the main participants in the majority of biological events, are both potential biomarkers and ther...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD043874 | Pride
Intraductal prostate carcinoma Proteomics Cribriform Liquid chromatography mass spectrometry Urinary extracellular vesicles 
UnknownIdentifying Urinary and Serum Exosome Biomarkers for Radiation Exposure Using a Data Dependent Acquisition and SWATH-MS Combined Workflow.
Not available
S-EPMC5042854 | biostudies-literature
ProteomicsProteomic Discovery and Array-Based Validation of Biomarkers from Urinary Exosome by Supramolecular Probe
Exosomes are nanoscale, membrane-enclosed vesicles with contents similar to their parent cells, which are rich in potential biomarkers, including membrane proteins such as transporters and receptors, transcription factors and microRNAs. Urine, as a non-invasive sampling body fluid, has the advantage...
ORGANISM(S): Homo Sapiens (human) 
2023-03-10 | PXD040756 | JPOST Repository
ProteomicsQuantitative proteomic analysis of urinary exosomes from patients with primary aldosteronism that underwent fludrocortisone suppression test
The sodium chloride cotransporters (NCC) and the epithelial sodium channel (ENaC) have been reported to be the main effectors of aldosterone in Na+ and Cl- reabsorption in the distal nephron and dietary K+ downregulates NCC. The Cl-/HCO3- exchanger pendrin has been revealed as a key role in maintain...
ORGANISM(S): Homo sapiens (Human) 
2020-11-20 | PXD017083 | Pride
Human Exosomes Urine Kidney 
UnknownHuman urinary exosomes as innate immune effectors.
Not available
S-EPMC4147985 | biostudies-literature
ProteomicsMultiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach
The recent advance in targeted label-free proteomics, SWATH-MS, can provide consistent protein detection and reproducible protein quantitation, which is a considerable advantage for biomarker study of urinary exosome-enriched extracellular vesicles (EVs). We developed a SWATH-MS workflow with a cura...
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD008891 | Pride
Biomarker  exosomes  human urine  microvesicles  post-acquisition data extraction  proteome 
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