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TranscriptomicsTranscriptional analysis of normal and pathological synovial fibroblasts
The aim of this study was to compare gene expression between two pathological groups of human synovial fibroblasts (SF) from rheumatoid arthritis (RA) and osteoarthritis (OA) synovial tissues with normal SF from healthy individuals (HSF). We used microarray expression profiling in SF cultured from ...
ORGANISM(S): Homo sapiens 
2011-10-24 | E-GEOD-29746 | biostudies-arrayexpress
TranscriptomicsTranscriptional response to hypoxia of normal and rheumatoid arthritis synovial fibroblasts
Inflammatory tissues are characterized by low oxigen concentrations (hypoxia). These conditions are very different from that usually present in tissue cultures where transcriptomic profiles of human fibroblasts from inflammatory tissues have been previously analysed. The aim of this study was to cha...
ORGANISM(S): Homo sapiens 
2010-12-10 | E-GEOD-21959 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profile in macrophages from rheumatoid arthritis and osteoarthritis patients
In osteoarthritis (OA) and rheumatoid arthritis (RA), many pathological alterations result from aberrant macrophage hyperactivation in the inflamed synovial membrane, and inhibition of macrophage effector functions is a therapeutic strategy in both diseases. Little is known, about the specific gene...
ORGANISM(S): Homo sapiens 
2016-02-05 | E-GEOD-63745 | biostudies-arrayexpress
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