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TranscriptomicsExpression data of cHL cell lines after KLF4 activation
Characteristic extinguishing of B-cell phenotype in cHL is believed to be a result of transcription factor network deregulation due to the overexpression of repressor proteins ID2 and ABF-1. KLF4 is a versatile transcription factor, participating in regulation of differentiation processes in various...
ORGANISM(S): Homo sapiens 
2010-10-22 | E-GEOD-21296 | biostudies-arrayexpress
TranscriptomicsExpression data of cHL cell lines after FOXO1 activation
FOXO1 is highly expressed in normal B cells and in most types of non-Hodgkinl lymphoma. In Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma(cHL) expression of FOXO1 is low or absent. We overexpressed constitutively active mutant of FOXO1 fused in frame with estrogen receptor ligand-bin...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-29545 | biostudies-arrayexpress
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