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ProteomicsProteomic characterization of ubiquitin carboxyl-terminal hydrolase 19 deficient cells reveals a role for USP19 in secretion of lysosomal proteins
Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a unique deubiquitinase (DUB), characterized by multiple variants generated by alternative splicing. Several variants bear a C-terminal transmembrane domain that anchors them to the endoplasmic reticulum (ER). Other than regulating protein stabilit...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055081 | Pride
Lysosome Cathepsins. Ubiquitin carboxyl-terminal hydrolase 19  proteomics  unconventional secretion  secretome  legumain 
ProteomicsProteomic characterization of ubiquitin carboxyl-terminal hydrolase 19 deficient cells reveals a role for USP19 in secretion of lysosomal proteins
Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a unique deubiquitinase (DUB), characterized by multiple variants generated by alternative splicing. Several variants bear a C-terminal transmembrane domain that anchors them to the endoplasmic reticulum (ER). Other than regulating protein stabilit...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055064 | Pride
Lysosome Cathepsins. Ubiquitin carboxyl-terminal hydrolase 19  proteomics  unconventional secretion  secretome  legumain 
ProteomicsProteomic characterization of ubiquitin carboxyl-terminal hydrolase 19 deficient cells reveals a role for USP19 in secretion of lysosomal proteins
Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a unique deubiquitinase (DUB), characterized by multiple variants generated by alternative splicing. Several variants bear a C-terminal transmembrane domain that anchors them to the endoplasmic reticulum (ER). Other than regulating protein stabilit...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055118 | Pride
Lysosome Cathepsins. Ubiquitin carboxyl-terminal hydrolase 19  proteomics  unconventional secretion  secretome  legumain 
GenomicsUSP19 and RPL23 as candidate prognostic markers in advanced-stage high-grade serous ovarian carcinoma
USP19 and RPL23 as candidate prognostic markers in advanced-stage high-grade serous ovarian carcinoma
PRJNA697947 | ENA
UnknownUSP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
Not available
S-EPMC8674369 | biostudies-literature
UnknownUSP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
Not available
S-EPMC5133830 | biostudies-literature
UnknownThe USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2.
Not available
S-EPMC3195621 | biostudies-literature
UnknownUSP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling.
Not available
S-EPMC4342027 | biostudies-literature
TranscriptomicsUSP19 and RPL23 as candidate prognostic markers in advanced-stage high-grade serous ovarian carcinoma
Ovarian cancer is one of the leading causes of death among patients with gynecological malignancies worldwide. To identify prognostic markers for ovarian cancer, we performed RNA-sequencing and analyzed the transcriptome data from 51 patients who received conventional therapies for high-grade serous...
ORGANISM(S): Homo sapiens 
2021-08-09 | GSE165808 | GEO
UnknownUSP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth.
Not available
S-EPMC6353870 | biostudies-literature
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