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Nocardia seriolae UTF1 Genome Sequencing
CDC14 phosphatases are critical components of the cell cycle machinery that drives exit from mitosis in yeast. However, the two mammalian paralogs, CDC14A and CDC14B, are dispensable for cell cycle progression or exit, and their function remains unclear. By generating a double Cdc14a; Cdc14b-null mo...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-10-31 | PXD030296 | Pride
Pluripotent stem cells retain the ability differentiate into the three germ layers and germ line. As a result, there is a major interest in characterizing regulators that establish and maintain pluripotency. The network of transcription factors continues to expand in complexity, and one factor, Undi...
ORGANISM(S): Mus musculus 
Promoter methylation profiles are proposed as potential prognosis and/or diagnosis biomarkers in cervical cancer. Up to now, little is known about the promoter methylation profile and expression pattern of stem cell (SC) markers during tumor development. In this study, we were interested to identify...
ORGANISM(S): Homo sapiens 
2012-03-21 | GSE36637 | GEO
The core pluripotency factors (Oct4, Sox2, and Nanog), the Myc network, and the chromatin-modifying complexes such as PRC2 ensure the pluripotency and self-renewal of ES cells (ESC). How these factors coordinate with one another remains poorly understood. We report that Utf1, a target of Oct4 and So...
ORGANISM(S): Mus musculus 
Mammalian CDC14 control differentiation from pluripotent cells by modulating UTF1 activity on bivalent promoters
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