Vaccine development

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Unknown (22072)
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Organisms

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Organisms

Homo sapiens (140)
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unidentified (3)
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Norovirus (2)
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Macaca fascicularis (2)
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Bordetella pertussis (2)
Influenza A virus (2)
Streptococcus pneumoniae (2)
Salmonella enterica subsp. enterica serovar Typhimurium (2)
Enterococcus faecalis (2)
Oncorhynchus mykiss (2)
Solanum lycopersicum (2)
Giardia duodenalis (2)

Repository

ENA (743)
geo (302)
biostudies-arrayexpress (188)
pride (103)
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Technology Type

Mass Spectrometry (103)
Shotgun proteomics (52)
Mass spectrometry (15)
Bottom-up proteomics (14)
Affinity purification coupled with mass spectrometry proteomics (11)
Data-dependent acquisition (10)
Gel-based experiment (8)
SWATH MS (6)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
Data-independent acquisition (5)
NMR spectroscopy (2)
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Illumina HiSeq 2000 (1)
Glycoproteomics (1)
Immunopeptidomics (1)
MSE (1)
Top-down proteomics (1)

Instrument Platform

Orbitrap Fusion Lumos (8)
Illumina NovaSeq 6000 (7)
Illumina HiSeq 2000 (5)
Q Exactive HF (4)
Illumina MiSeq (3)
NextSeq 500 (3)
Orbitrap Eclipse (3)
Q Exactive HF-X (3)
Jencons Millennium CO2 Incubator (2)
Illumina HiSeq 2500 (2)
Illumina HiSeq 4000 (2)
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Chromium Single Cell 5' Library & Gel Bead Kit v2 (1)
FLOQSwab (Copan) (1)
MA900, Sony (1)
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UCHC CAM HPC cluster (1)
Genetix aQuire (1)
AB SOLiD System 3.0 (1)
GeneQuant (1)
NanoDrop (1)
Axon- GenePix4000B (1)
Bellco roll-in incubator (1)
NextSeq 1000 (1)
Illumina HiSeq X (1)
10x Genomics Chromium Controller (1)
Ion Torrent S5 XL (1)
Illumina HiSeq 1500 (1)
NextSeq 550 (1)

Publication Date

2025 (90)
2022 (64)
2023 (59)
2024 (57)
2021 (48)
2026 (44)
2013 (33)
2010 (33)
2020 (31)
2014 (28)
2016 (27)
2012 (25)
2011 (25)
2019 (21)
2018 (18)
2009 (17)
2015 (16)
2008 (16)
2017 (14)
2005 (5)
2007 (3)
2006 (1)

UNIPROT ID/AC

5833.MAL13P1.267 (2)
5833.MAL13P1.269 (2)
5833.MAL13P1.325 (2)
5833.MAL13P1.334 (2)
5833.MAL7P1.78 (2)
5833.MAL8P1.208 (2)
5833.MAL8P1.320 (2)
5833.PF11_0033 (2)
5833.PF11_0263 (2)
5833.PF11_0512 (2)
5833.PF13_0305 (2)
5833.PF13_0321 (2)
5833.PF14_0001 (2)
5833.PF14_0009 (2)
5833.PF14_0173 (2)
5833.PF14_0734 (2)
5833.PF14_0751 (2)
5833.PF14_0756 (2)
5833.PF14_0759 (2)
5833.PFA0105w (2)
5833.PFA0120c (2)
5833.PFA0705c (2)
5833.PFB0050c (2)
5833.PFB0280w (2)
5833.PFB0925w (2)
5833.PFB0946c (2)
5833.PFC1011c (2)
5833.PFC1075w (2)
5833.PFD0075w (2)
5833.PFD0100c (2)

CHEBI ID

CHEBI:15428 (4)
CHEBI:18012 (4)
CHEBI:17992 (3)
CHEBI:17822 (3)
CHEBI:22660 (3)
CHEBI:18257 (3)
CHEBI:16708 (3)
CHEBI:24898 (3)
CHEBI:25017 (3)
CHEBI:17754 (3)
CHEBI:15741 (3)
CHEBI:15940 (3)
CHEBI:27266 (3)
CHEBI:16449 (3)
CHEBI:30769 (3)
CHEBI:20067 (3)
CHEBI:17842 (2)
CHEBI:35490 (2)
CHEBI:30805 (2)
CHEBI:16113 (2)
CHEBI:33508 (2)
CHEBI:50129 (2)
CHEBI:26271 (2)
CHEBI:25094 (2)
CHEBI:16856 (2)
CHEBI:18237 (2)
CHEBI:16040 (2)
CHEBI:27570 (2)
CHEBI:30751 (2)
CHEBI:18186 (2)

Metabolite Name

Histidine (3)
Glycine (3)
Valine (3)
Succinic acid (3)
Citric acid (3)
Tyrosine (3)
Adenosine (3)
Alanine (3)
Glutamic acid (3)
Uridine (3)
Sucrose (3)
Trehalose (3)
Hypoxanthine (3)
Caracurine V (2)
(+)-Prosopinine (2)
9-F1-phytoprostane (2)
Cinnamic acid (2)
Margaric acid (2)
Sulfolithocholylglycine (2)
Lactic acid (2)
Anserine (2)
Phosphoric acid (2)
Leucine (2)
Glycerol (2)
Phthalic acid (2)
Uracil (2)
Ethotoin (2)
Pyroglutamic acid (2)
Carnosine (2)
Paxilline (2)

First Public Date

2025 (122)
2024 (99)
2023 (78)
2026 (71)
2022 (64)
2013 (51)
2021 (48)
2014 (47)
2020 (46)
2019 (29)
2018 (27)
2017 (26)
2015 (20)
2016 (11)
2010 (2)
2012 (1)
2011 (1)

Modelling Approach

Ordinary differential equation model (4)
Constraint-based model (2)
Markov model (1)

Study status

Active, not recruiting (1)
Recruiting (1)
Completed (1)

Lab affiliation

Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (5)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia. (3)
Boston University Medical Campus 670 Albany St., Rm. 509 Boston, MA 02118 USA (2)
Departamento de Ciências Biológicas, Laboratório de Enzimologia e Proteômica, Universidade Federal de Ouro Preto, Brazil (2)
Deputy Head (Research), Department of Biochemistry and Molecular Biology Head Immunoproteomics Laboratory Infection and Immunity Program Room 214, level 2, 15 Innovation Walk Monash Biomedicine Discovery Institute Monash University, Clayton Campus Clayton 3800 Victoria Australia (2)
Huazhong Agricultural University (2)
Instituto de Nanobiotecnologıa (NANOBIOTEC), UBA-CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina (2)
1- Department of Biology, Faculty of Science, Erciyes University, Kayseri, Turkey 2- Genome and Stem Cell Center (GENKÖK) Erciyes University, Kayseri, Turkey (1)
1.Department of Biochemistry, Faculty of Science, Kasetsart University, 50 Ngam Wong Wan Road, Chatuchak, Bangkok 10900, Thailand 2.Center for Advanced Studies in Nanotechnology for Chemical, Food and Agricultural Industries, KU Institute for Advanced Studies, Kasetsart University, Bangkok, 10900, Thailand (1)
1.Precision Vaccines Program, Division of Infectious Diseases, Boston Children’s Hospital, Boston, MA, USA. 2. Department of Pediatrics, Harvard Medical School, Boston, MA, USA. (1)
1Gavin Herbert Eye Institute –Brunson Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, University of California Irvine, Irvine, CA 92697, USA 2Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA 3Department of Chemistry, University of California Irvine, Irvine, CA 92697, USA 4Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, USA (1)
225, Veterinary Medical Center University of Minnesota 1365, Gortner Avenue St. Paul, MN 55108 (1)
Additional Professor, Deptt. of Medical Oncology (Lab), Dr BRAIRCH, AIIMS, New Delhi (1)
Associate Professor | Department of Pharmaceutical Sciences | College of Pharmacy | Oregon State University (1)
CEA-Marcoule, ProGénoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Cèze, France (1)
Center for Proteomics and Metabolomics, Leiden University Medical Center Leiden, the Netherlands (1)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Akademika Heyrovského 1203/8 500 05 Hradec Králové, Czech Republic (1)
College of Animal Science and Technology, Guangxi University, Nanning,China (1)
College of Life and Health Sciences, Northeastern University (1)
DCR (1)
Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA (1)
Department of Infection Biology Institute of Infection & Global Health University of Liverpool Liverpool Science Park IC2 146 Brownlow Hill Liverpool L3 5RF UK (1)
Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool. Liverpool, UK. (1)
Department of Medicine, Weill Cornell Medicine, New York, NY, USA (1)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (1)
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037 United States (1)
Department of Pediatrics, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA (1)
Department of Peptide-based Immunotherapy (1)
Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon 97331, USA (1)
Department of Pharmacy, University of Copenhagen (1)

Keyword

All types metastatic cancer where at least one tumor lesion is accessable for percutaneous cryoablation (1)
GI cancer (1)
Poly ICLC (1)
Vaccines (1)
Kidney cancer (1)

IsPrivate

False (9)

Model Flag

Non Kinetic (3)

Classification

bacteria (53)
viruses (25)
protozoa (14)
helminths (8)
fungi (1)

Modification

15.994915 (1)
42.010565 (1)
57.021464 (1)
Not available (1)

Study type

Transcription profiling by array (131)
RNA-seq of coding RNA (24)
Proteomic profiling by array (6)
RNA-seq of coding RNA from single cells (5)
Human - One-color microarray (4)
Comparative genomic hybridization by array (3)
Interventional (3)
Unknown experiment type (2)
Cell line - High-throughput sequencing (2)
Transcription profiling by tiling array (2)
Other (2)
RNA-seq of total RNA (2)
Animal - High-throughput sequencing (1)
ATAC-seq (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (3022)
2021 (2753)
2023 (2536)
2024 (2027)
2025 (2026)
2020 (1887)
2019 (1192)
2018 (1096)
2017 (895)
2016 (796)
2015 (751)
2014 (688)
2013 (468)
2012 (373)
2011 (328)
2010 (299)
2026 (235)
2009 (208)
2008 (177)
2007 (125)
2006 (88)
2005 (82)
2004 (47)
2003 (34)
2000 (30)
2001 (29)
2002 (26)
1999 (21)
1998 (16)
1997 (4)

Location

United States (2)
Puerto Rico (1)
China (1)

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Research on vaccine immunity based on gut microbiota and metabolomics The impact of pseudorabies virus infection

Pseudorabies virus infection causes intestinal flora disorder in animals, leading to diarrhea. To explore the effect of inactivated pseudorabies vaccine immunization on pseudorabies virus infection, this study sequenced the serum metabolome and intestinal microbiota of Hu sheep, analyzed their di...

2025-09-03 | MTBLS12933 | MetaboLights

Research on vaccine immunity based on gut microbiota and metabolomics The impact of pseudorabies virus infection

2025-09-04 | MTBLS12936 | MetaboLights

RA-MAP: mapping the molecular immunological landscape in early rheumatoid arthritis with vaccine controls

Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of RA, we performed comprehensive clinical and molecu...

2021-06-16 | MTBLS1497 | MetaboLights

Deep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights

Immunosignatures can predict vaccine efficacy

Mice were immunized with either formalin fixed Influenza A/PR/8/34 (Killed PR8), the 2006-2007 seasonal influenza vaccine, the 2007-2008 seasonal influenza vaccine, a sublethal infection (live PR8) or mock immunized (PBS). Array data was used to distinguish the immunogens from each other and predic...

ORGANISM(S): Mus musculus

2013-11-04 | E-GEOD-51623 | biostudies-arrayexpress

Affect of antiviral ribavirin on YFV WT and vaccine strains.

Live-attenuated viral vaccines have been successfully used to combat infectious disease for decades but due to their empirical derivation, little is known about their mechanisms of attenuation. This lack of understanding makes the development of next generation live attenuated vaccines difficult. Th...

ORGANISM(S): Yellow fever virus

2020-01-01 | E-MTAB-8504 | biostudies-arrayexpress

Trivalent Inactivated Influenza Vaccine (TIV) and Live Attenuated Influenza Vaccine (LAIV) Induce Different B cell and Transcriptional Responses in Children

LAIV and TIV are effective for prevention of influenza infection in children, but the mechanisms associated with protection are still not well defined. We analyzed the differences in B cell responses and transcriptional profiles. Compared to baseline, LAIV elicited a significant increase in naM-CM-/...

ORGANISM(S): Homo sapiens

2014-03-31 | E-GEOD-52005 | biostudies-arrayexpress

Priorities for CMV vaccine development.

Not available

S-EPMC4623576 | biostudies-literature

Gene expression profiling after vaccination with the RTS,S candidate malaria vaccine in a controlled human malaria infection study

RTS,S is the sole candidate vaccine shown to provide protection against infection to malaria-naive adults challenged with mosquito-borne homologous falciparum malaria and protection against infection and clinical and severe disease to volunteers in malaria-endemic Africa who were exposed to diverse ...

ORGANISM(S): Homo sapiens

2017-04-27 | E-MTAB-4629 | biostudies-arrayexpress

Dissecting the Mycobacterium bovis BCG response to macrophage infection to identify targets for anti-tuberculosis drug and vaccine discovery

New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of Mycobacterium tuberculosis after macrophage phagocytosis is a fundamental step in the complex host-pathogen interactions that lead to granuloma formation and disease. Greater underst...

ORGANISM(S): Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2

2022-01-14 | E-MTAB-11107 | biostudies-arrayexpress

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