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ProteomicsDepletion of Keratin8 affects tumorigenic potential of A431 cells via altering multiple signaling pathways
Keratins are the largest subgroup of intermediate filament proteins which are expressed in a tissue specific and differentiation state dependent manner. Apart from their mechanical functions, they have been shown to perform various regulatory roles. Most of these functions have been studied on ker...
ORGANISM(S): Homo sapiens (Human) 
2018-02-27 | PXD007206 | Pride
Human Quantitative proteomics Tmt Skin-scc Keratin 8 
ProteomicsQuantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation on Keratin-8 in skin squamous cell carcinoma derived cell-line
The epithelial specific keratin pair, Keratin 8/18 (K8/18), has been reported to be aberrantly expressed in squamous cell carcinoma (SCC) which is also correlated with increased invasiveness and poor prognosis. A Majority of Keratin 8 (K8) functions are governed by its phosphorylation at Serine73 (...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005301 | Pride
Keratin 8 phosphorylation Tmt based quantitative phosphoproteomics Human epidermoid carcinoma cell-line 
UnknownFetal thyroid hormone level at birth is associated with fetal growth.
Not available
S-EPMC3100744 | biostudies-literature
UnknownBioassay directed isolation and biological evaluation of compounds isolated from Rubus fairholmianus Gard.
Not available
S-EPMC4165380 | biostudies-literature
UnknownThe synthesis of alternating donor-acceptor polymers based on pyrene-4,5,9,10-tetraone and thiophene derivatives, their composites with carbon, and their lithium storage performances as anode materials.
Not available
S-EPMC8698373 | biostudies-literature
UnknownPlasminogen Activator Inhibitor-1 and Pericardial Fat in Individuals with Type 2 Diabetes Mellitus.
Not available
S-EPMC5564011 | biostudies-literature
UnknownEffect of heart failure reversal treatment as add-on therapy in patients with chronic heart failure: A randomized, open-label study.
Not available
S-EPMC5485380 | biostudies-literature
UnknownGene expression analysis reveals the cell cycle and kinetochore genes participating in ischemia reperfusion injury and early development in kidney.
Not available
S-EPMC3181346 | biostudies-literature
UnknownInferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements.
Not available
S-EPMC6278976 | biostudies-literature
TranscriptomicsEffect of anti-IL-15 administration on T cell and NK cell homeostasis in rhesus macaques (TCM)
Analysis of the effect of anti-IL-15 monoclonal antibody treatment on T cell and NK cell homeostasis in rhesus macaques. The hypothesis tested in the present study was that repeated administrations of a rhesusized anti-IL-15 monoclonal antibody would block IL-15 activity in vivo and result in change...
ORGANISM(S): Macaca mulatta 
2016-09-07 | E-GEOD-76785 | biostudies-arrayexpress
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