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TranscriptomicsComparison of pan-inhibitor of HDACS (TSA) to specific HDAC8 inhibitor (HDAC Inhibitor XIX, Compound 2) in human myometrium
To compare gene expression in human myometrium after TSA treatment to gene expression after treatment with a specific HDAC8 inhibitor Four Control, four TSA and four Compound 2 samples (2 patients, replicated) derived from non-pregnant myometrial strips
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-27124 | biostudies-arrayexpress
TranscriptomicsRNA messengers translated at the ER membrane
In order to identify what RNA messengers are being translated at the ER membrane, membrane-associated polysomes were separated from free polysomes by subcellular fractionation of WT and delta-egd1/delta-egd2 yeast strains and associated RNA was isolated and then identified by microarray analysis. Se...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45795 | biostudies-arrayexpress
TranscriptomicsRNA coimmunoprecipitations
Nascent polypeptides emerging from the ribosome during biogenesis can interact with many chaperones and protein homeostasis factors. The high sensitivity of RNA identification can be used to identify substrates of specific cotranslationally acting chaperones. Protein A-tagged (TAP-tag) chaperones as...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45794 | biostudies-arrayexpress
TranscriptomicsFunctional categorization of transcriptome in the species Symphysodon aequifasciatus Pellegrin 1904 (Perciformes: Cichlidae) exposed to benzo[a]pyrene and phenanthrene
This study aims to evaluate the transcriptome alterations, through cDNA libraries, associated with the effects of the combination of two PAHs, benzo[a]pyrene (0.5M-NM-
ORGANISM(S): Symphysodon aequifasciata 
2013-12-09 | E-GEOD-51149 | biostudies-arrayexpress
TranscriptomicsPolysomes
Translational profiles of wild type yeast strains were identified by microarray analysis by isolating polysomes using sucrose gradients to recover polysome-associated RNA and comparing polysome-associated RNA vs total RNA Set of arrays that are part of repeated experiments
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-05 | E-GEOD-45797 | biostudies-arrayexpress
UnknownMapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex.
Not available
S-EPMC2952226 | biostudies-literature
UnknownPeptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding.
Not available
S-EPMC3801073 | biostudies-literature
UnknownAnalysis of human C1q by combined bottom-up and top-down mass spectrometry: detailed mapping of post-translational modifications and insights into the C1r/C1s binding sites.
Not available
S-EPMC2860232 | biostudies-literature
MetabolomicsPhysiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes
Human metabolism is highly variable. At one end of the spectrum, defects of enzymes, transporters, and metabolic regulation result in metabolic diseases such as diabetes mellitus or inborn errors of metabolism. At the other end of the spectrum, favorable genetics and years of training combine to res...
2022-02-07 | MTBLS2104 | MetaboLights
TranscriptomicsTranscriptomic alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi
We examined the extent to which different Trypanosoma cruzi strains induce transcriptomic changes in cultured L6E9 myoblasts 72 hours or 48 hours after infection with four strains of the parasite [Brazil (TCI); Y, CL and Tulahuen (TC II) strains]. Expression of 6,289 distinct fully annotated unigene...
ORGANISM(S): Rattus norvegicus 
2009-09-22 | E-GEOD-18175 | biostudies-arrayexpress
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