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TranscriptomicsMolecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival
Understanding the role of host factors during lethal influenza virus infection is critical to deciphering the events that will determine the fate of the host. One such factor is encoded by the Mx1 gene, which confers resistance to influenza virus infection. Here, we compared pathology and global gen...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-35933 | biostudies-arrayexpress
UnknownMulticenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy.
Not available
S-EPMC6209089 | biostudies-literature
TranscriptomicsFunctional genomics of central nervous system and liver following herpes simplex virus corneal infection.
The overall goal of the study was to use in vivo data combined with functional genomics to define gene expression signatures representative of a spectrum of HSV CNS infections. Innate immune deficiencies result in a spectrum of severe clinical outcomes following infection. In particular, there is a ...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-35943 | biostudies-arrayexpress
TranscriptomicsThe effect of alpha, beta, gamma interferon receptors on host reponse to influenza virus in mouse embryonic fibroblasts
The objective of this study was to examine the host transcriptional response to high and low pathogenecity viruses in mouse embryonic fibroblasts (MEFs) isolated from different mouse genetic backgrounds to further understand the contribution of interferon signaling pathways to host response to influ...
ORGANISM(S): Mus musculus 
2012-04-29 | E-GEOD-37665 | biostudies-arrayexpress
GenomicsEGAS00000000092-ega-27092011 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000044 | EGA
GenomicsEGAS00000000092-ega-20110419 2 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000023 | EGA
GenomicsEGAD00010000280
CLL Expression array
EGAD00010000280 | EGA
GenomicsEGAD00010000238
CLL Expression array
EGAD00010000238 | EGA
Genomics20ExonArrays_EGAS00000000092 - samples
CLL Expression Array
EGAD00010000470 | EGA
GenomicsCLL Genome
The Chronic Lymphocytic Leukemia (CLL) Genome Project aims to identify genetic alterations involved in the development and progression of the CLL, which are still unknown, with the objective of generating a comprehensive catalogue of genetic alterations in 500 independent tumours. The CLL Genome Pro...
EGAS00000000092 | EGA
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