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ProteomicsModulation of the ATM / autophagy pathway tips the balance between senescence and apoptosis in response to a quadruplex ligand
G-quadruplex ligands (G4L) exert their anti-proliferative effect through telomere-dependent and -independent mechanisms, but the inter-relationship between autophagy, cell growth arrest and cell death induced by these ligands remains largely unexplored. 20A is a 2,4,6-triarylpyridine derivative that...
ORGANISM(S): Homo sapiens (Human) 
2019-02-19 | PXD009430 | Pride
G4  quadruplex ligand  autophagy  senescence  apoptosis  triarylpyridine  antiproliferative agents  label-free quantitative proteome analysis. 
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