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Transcriptome analysis of valosin-containing protein effect on cardiac hypertrophy and dysfunction
Valosin‐containing protein (VCP)/p97/Cdc48 is an essential AAA+ ATPase associated with many ubiquitin-dependent cellular pathways that plays a central role in protein quality control in all eukaryotes. Its functional diversity relies on its ability to cooperate with a large number of protein cofacto...
ORGANISM(S): Leishmania infantum JPCM5 
2020-08-06 | PXD013731 | Pride
This sstudy was designed to investigate the gene netweork regulated by valosin-containing protein (VCP), an ATPase-associated protein, whic acts as a novel regulator against the cardiac stress of pressure overload. We performed transcriptome analyses to compare cardiac-specific VCP overexpression tr...
ORGANISM(S): Mus musculus 
2020-09-24 | GSE134085 | GEO
Study of the effects of the VCP knockdown. VCP (p97, yeast cdc48) is a hexameric AAA ATPase involved in various cellular functions including degradation of proteins by the ubiquitin-proteasome system. We examine the consequences of the reduction of VCP levels after RNAi of VCP in HeLa cells. We find...
ORGANISM(S): Homo sapiens 
Loss of Small Valosin-containing Protein-Interacting Protein (SVIP) in Rat Hepatoma cells Causes Increased Intracellular Retention of Very Low-Density Lipoproteins (VLDL)
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