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GenomicsDistribution of Drosophila insulator proteins Mod(mdg4) and L(3)mbt in Kc cells
Here we map the localization of Mod(mdg4), including Mod(mdg4)2.2 specific and Mod(mdg4) common to all isoforms, to chromatin insulators, as well as the lethal-3 malignant brain tumor protein in Drosophila Kc cells. examination of genomic occupancy for Mod(mdg4)2.2, Mod(mdg4)BTB (all isoforms), and ...
ORGANISM(S): Drosophila melanogaster 
2012-06-18 | E-GEOD-36393 | biostudies-arrayexpress
GenomicsDistribution of histone modificiation H3K27me3 in Drosophila Kc cells, comparison with dCTCF knockdown
Here we map the localization of H3K27me3 in Drosophila Kc cells, as well as in Drosophila Kc cells wherein dCTCF is knock down. examination of genomic occupancy for H3K27me3, control samples used for Drosophila Kc were previously described (Wood, Van Bortle et al., 2011 GSE30740)
ORGANISM(S): Drosophila melanogaster 
2012-06-18 | E-GEOD-37444 | biostudies-arrayexpress
GenomicsDistribution of insulator proteins CP190, dCTCF, Su(Hw) and Mod(mdg4)2.2 in Drosophila S2 cells in the presence or absence of dPARP inhibitor 3AB
We mapped the localization of insulator proteins in Drosophila S2 cells in the presence or absence of 12mM of 3AB. We found that inhibition of PARylation affects DNA binding of insulator proteins only at a small subsets of genomic sites. Examination of genomic occupancy for insulator proteins in S2 ...
ORGANISM(S): Drosophila melanogaster 
2013-09-15 | E-GEOD-41354 | biostudies-arrayexpress
ProteomicssnaR-A RNA pulldown LC-MS for identification of RNA binding proteins
RNA polymerase III (Pol III) activity in cancer is linked to the production of small noncoding (nc)RNAs that are otherwise silent in most tissues. snaR-A (small NF90-associated RNA isoform A) - a hominid-specific ncRNA shown to enhance cell proliferation, migration, and invasion - is a cancer-emerge...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD054429 | Pride
Snar-a Lc-ms Rnapulldown 
GenomicsHistone Phosphoacetylation ChIP-seq of Kc167 cells from Drosophila
ChIP-seq was performed using Drosophila Kc167 cells using antibodies against H3K4me3 to identify active promoters and H3K4me1 to identify active enhancers. H3K27ac ChIPseq was performed to identify active promoters and enhancers. Once enhancers and promoters were identified, JIL-1 and histone phosph...
ORGANISM(S): Drosophila melanogaster 
2012-03-29 | E-GEOD-36374 | biostudies-arrayexpress
GenomicsDistribution of Drosophila insulator proteins after ecdysone treatment in Kc cells
Here we examine changes in the distribution of Drosophila insulator proteins during the ecdysone response. We performed ChIP-seq analysis in Kc cells at 0, 3, and 48 hours of ecdysone treatment with antibodies against CP190, Su(Hw), dCTCF, and BEAF-32B. Examination of 4 different insulator proteins...
ORGANISM(S): Drosophila melanogaster 
2011-10-13 | E-GEOD-30740 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Kc cells from Drosophila melanogaster during ecdysone treatment and CP190 knockdown
This study examines the changes in genes expression that occur in Drosophila melanogaster during the ecdysone response as well as during RNAi knockdown of the insulator protein, CP190. Analysis was performed in Kc cells after 0, 3, and 48 hours of ecdysone treatment in the presence of either contro...
ORGANISM(S): Drosophila melanogaster 
2011-10-13 | E-GEOD-30686 | biostudies-arrayexpress
GenomicsChIP-seq mapping of Drosophila TFIIIC (dTFIIIC220; CG7099) and SMC containing complexes in Kc167 cells
We map the genome-wide binding profiles for dTFIIIC220, as well as the Drosophila cohesin and condensin complexes in the late-stage embryonic cell line Kc167 Examination of several proteins in the Kc167 cell line
ORGANISM(S): Drosophila melanogaster 
2014-05-14 | E-GEOD-54529 | biostudies-arrayexpress
GenomicsCTCF and Smad signaling proteins and response to DPP
ChIP-seq profiles for CTCF and TGF-beta signaling factors before and after treatment with DPP Examination of transcription factor dynamics during signaling
ORGANISM(S): Drosophila melanogaster 
2015-05-08 | E-GEOD-68654 | biostudies-arrayexpress
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