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Liver fibrosis is characterized by the excessive formation and accumulation of matrix proteins as a result of wound healing in the liver. A main event during fibrogenesis is the activation of the liver resident quiescent hepatic stellate cell (qHSC). Recent studies suggest that reversion of the acti...
ORGANISM(S): Homo sapiens 
A double-blind, placebo-controlled, cross-over trial was undertaken in people with T2D, who were administered 1000mg/day ascorbic acid or placebo for 4-months. Plasma proteins in 26 participants (22 male, 4 female, age 62.6±6.5 years, HbA1c 7.6±0.7%) were quantified by liquid chromatography/mass sp...
ORGANISM(S): Homo sapiens (Human) 
2026-07-02 | PXD068613 | Pride
Early during culture of primary mouse HSCs gene expression changes. These expression alterations can be affected by treating cells with histone deacetylase inhibitor, valproic acid Primary mouse Hepatic stellate cells were cultured for short periods of time (4-16-64h) in presence or absence of valpr...
ORGANISM(S): Mus musculus 
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