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TranscriptomicsTranscription profiling of rat pancreatic islets after culture in low, intermediate and high [glucose]
Background: Survival and function of insulin-secreting pancreatic β-cells are markedly altered by changes in nutrient availability. In vitro, culture in 10 rather than 2mM glucose improves rodent β-cell survival and function whereas glucose concentrations above 10mM are deleterious. Aim-Method: T...
ORGANISM(S): Rattus norvegicus 
2009-01-31 | E-GEOD-12817 | biostudies-arrayexpress
TranscriptomicsExpression data from normal and transplanted islets in non-pregnant and pregnant condition
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59143 | biostudies-arrayexpress
TranscriptomicsLow dose human chorionic gonadotropin hCG
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-10-02 | E-GEOD-18557 | biostudies-arrayexpress
TranscriptomicsCOX-2 network as predictive molecular marker for clinical pregnancy in IVF
CONTEXT Nowadays, the molecular mechanisms involved in endometrial receptivity and implantation are still not clear. OBJECTIVE The gene expression of human endometrium of patients undergoing an IVF treatment with GnRH antagonists/rec-FSH was studied. CONCLUSIONS COX-2 has been extensively studied ...
ORGANISM(S): Homo sapiens 
2010-09-06 | E-GEOD-18140 | biostudies-arrayexpress
TranscriptomicsExpression data from islets of non-pregnant and pregnant PRLR+/+ and PRLR-/- mice
ABSTRACT:Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we previously identified prolactin receptors ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-59141 | biostudies-arrayexpress
TranscriptomicsCOUP-TFII Controls Mouse Postnatal Pancreatic β-Cell Mass through GLP-1 β-Catenin
Pancreatic β-cells have the key homeostatic function of releasing insulin to keep blood glucose in the normal range. It is not fully understood how β-cell mass is determined. Ablation of a nuclear receptor, chicken ovalbumin upstream promoter transcription factor II (COUP-TFII), in mouse pancreat...
ORGANISM(S): Rattus norvegicus 
2011-10-06 | E-GEOD-30526 | biostudies-arrayexpress
TranscriptomicsTransciption profiling of human endometrial biopsies taken on the day of oocyte retrieval in stimulated IVF cycles with 1 or 2 embryos replaced on day 3 in the same cycle
In GnRH-antagonist/rec-FSH stimulated cycles, advanced endometrial maturation on the day of oocyte retrieval correlates with altered gene expression Experiment Overall Design: Endometrial biopsies taken on the day of oocyte retrieval in stimulated IVF cycles with 1 or 2 embryos replaced on day 3 in ...
ORGANISM(S): Homo sapiens 
2009-11-16 | E-GEOD-13027 | biostudies-arrayexpress
TranscriptomicsTranscription in adult mouse tissues
We used Affymetrix Gene Arrays (1.0 ST) to compare gene expression across different murine tissues. Arrays were used to find disallowed genes in tissues. Different tissues were dissected from 10-12 week old C57Bl6 mice for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-24940 | biostudies-arrayexpress
TranscriptomicsLow dose hCG pregnant vs non-pregnant
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-09-07 | E-GEOD-21225 | biostudies-arrayexpress
TranscriptomicsLarge-scale analysis of the mouse transcriptome
We used microarrays to compare gene expression across different murine tissues. Keywords: Other Different tissues were dissected from 10-12 week old C57Bl6 mice for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2007-12-20 | E-GEOD-9954 | biostudies-arrayexpress
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