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TranscriptomicsShort RNAs expression profiling in circulating CD34+ cells from Primary Myelofibrosis patients and from normal controls pooled bone marrow CD34+ cells.
We report the application of Illumina short RNA sequencing for characterization and discovery of miRNAs and moRNAs, and for identification of differentially expressed small RNAs in circulating CD34+ cells from Primary Myelofibrosis (PMF) patients and from normal controls pooled bone marrow CD34+ cel...
ORGANISM(S): Homo sapiens 
2016-03-17 | E-GEOD-69089 | biostudies-arrayexpress
TranscriptomicsShort RNAs expression profiling in SET2 cells.
We report the application of Illumina short RNA sequencing for characterization and discovery of miRNAs and moRNAs in SET2 cells carrying JAK2 V617F mutation. Short RNAs sequencing for miRNA quantification, discovery and characterisation.
ORGANISM(S): Homo sapiens 
2012-02-08 | E-GEOD-30672 | biostudies-arrayexpress
TranscriptomicsInhibition of Jak2 in SET2 cell line with INC424 (two time points and 3 dose levels in triplicate)
SET2 cells were incubated with increasing concentration of INC424/Ruxolitinib for 3-6 h and RNA was purified. Affymetrix Genechip miRNA array 2.0 was used to identify miRNA species showing a differential expression in treated cells compared with control cells. Exponentially growing SET2 cells were c...
ORGANISM(S): Homo sapiens 
2012-02-08 | E-GEOD-33809 | biostudies-arrayexpress
UnknownMyeloproliferative neoplasm (MPN) symptom assessment form total symptom score: prospective international assessment of an abbreviated symptom burden scoring system among patients with MPNs.
Not available
S-EPMC4872304 | biostudies-literature
TranscriptomicsIntegrative Analysis of Gene and miRNA expression profiles in Primary Myelofibrosis CD34+ cells
Ph-negative myeloproliferative neoplasms (MPNs) are characterized by many somatic mutations which have already been shown useful in the prognostic assessment of MPN patients. Moreover, aberrant microRNA (miRNA) expression seems to add to the molecular complexity of MPNs, as specific miRNA signatures...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-53482 | biostudies-arrayexpress
TranscriptomicsGene expression profile of mutated and wild-type PMF CD34+ cells
Primary mielofibrosis (PMF) is a rare chronic myeloproliferative disorder characterized by the accumulation of abnormal megakaryocytes (Mks) in the bone marrow (BM), variable degrees of BM fibrosis, osteosclerosis and angiogenesis, immature myeloid and erythroid cells, and tear-drop erythrocytes in ...
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-41812 | biostudies-arrayexpress
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