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MetabolomicsMapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variat...
2020-12-02 | MTBLS1188 | MetaboLights
MetabolomicsIntegrated metabolomics and transcriptomics analysis elucidate the candidate genes for polyphyllin biosynthesis in Paris

Polyphyllins are the key components in Paris, with varying levels and compositions among different species. This study investigated polyphyllin compositions of 206 Paris samples from 16 different producing areas. 9 Paris polyphylla var. yunnanensis, 3 Paris fargesii and 3 Paris forrestii were sel...

2024-10-18 | MTBLS10682 | MetaboLights
MetabolomicsInvestigating uncharacterised genes in Saccharomyces cerevisiae using Robot Scientists

Despite extensive research on Saccharomyces cerevisiae functional genomics, approximately 880 out of ~6,000 open reading frames (ORFs) remain uncharacterised. In this study we propose a method for characterising genes with limited prior functional knowledge using an automated laboratory platform,...

2025-12-03 | MTBLS12663 | MetaboLights
MetabolomicsThe effects of different rootstocks on aroma components, activities and genes expression of aroma-related enzymes in oriental melon fruit

Grafting is widely applied in the cultivation of melon. In this study, 'Qinmi No.1' [Cucumis melo L. (QG)] and 'Ribenxuesong' [Cucurbita maxima Duch. (RG)] were used as rootstocks for 'QingxinYangjiaocui' (Cucumis melo L.). The results showed that grafting with...

2023-11-21 | MTBLS8677 | MetaboLights
MetabolomicsIntegrated GWAS and metabolomic analyses identified metabolic pathways and candidate genes involved in free asparagine accumulation in durum wheat grain

Free asparagine content is a key factor in acrylamide formation in wheat derivatives after high temperature processing. Therefore, the control of free asparagine levels is of interest in crop and food sciences. Our study aims to explore the natural variation in durum wheat to identify candidate g...

2025-05-23 | MTBLS10381 | MetaboLights
ProteomicsComparative transcriptomic and proteomic analyses reveal multiple differences associated with albino leaves in Ananas comosus var. Bracteatus
Ananas comosus var. bracteatus has high ornamental value and widespread application because of its chimeric leaves. However, little is known about the molecular mechanism regulating this characteristic. Here, comparative transcriptomic and proteomic analyses of the white parts (Whs) and green parts ...
ORGANISM(S): Ananas comosus var. bracteatus 
2019-06-10 | PXD010375 | Pride
Molecular mechanism Chimeric leaves Proteome Ananas comosus var. bracteatus Transcriptome 
TranscriptomicsHP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster
Heterochromatin protein 1a (HP1a) is a chromatin associated protein that has been well studied in many model organisms, such as Drosophila, where it is a determining factor for classical heterochromatin. HP1a is associated with the two histone methyltransferases SETDB1 and Su(var)3-9, which mediate ...
ORGANISM(S): Drosophila melanogaster 
2013-04-05 | E-GEOD-43478 | biostudies-arrayexpress
TranscriptomicsMolecular Analysis of the Genes Involved in Aroma Synthesis in the Species S. cerevisiae, S. kudriavzevii and S. bayanus var. uvarum in Winemaking
This research work investigates the hybridization of the genes of Saccharomyces bayanus var. uvarum CECT 12600 and S. kudriavzevii IFO1802 employing S. cerevisiae microarrays. Two strains,one S. kudriavzevii and one S. bayanus var. uvarum were employed for the study. The S. cerevisiae strain S288C w...
ORGANISM(S): Saccharomyces uvarum 
2014-06-23 | E-GEOD-52446 | biostudies-arrayexpress
MetabolomicsTranscriptomic and Metabolomic Analysis Reveals Key Genes and Metabolites in Common Vetch (Vicia sativa L.) Response to Drought Stress

Common vetch (Vicia sativa L.) is an important annual leguminous forage crop commonly used for green manure, fodder, and soil improvement. It is widely cultivated as a green manure and forage crop in Yunnan Province during winter and spring. However, the dry conditions and minimal rainfall d...

2026-01-31 | MTBLS13368 | MetaboLights
TranscriptomicsSmall RNA sequencing of control and Su(var)3-7 mutant Drosophila ovary
Comparison of small RNA fractions derived from piRNA clusters and transposon sequences in control and Su(var)3-7 null mutant. Small RNA profile of 3-day old control and Su(var)3-7 mutant ovaries were generated by high-throughput sequencing on Illumina HiSeq 2000
ORGANISM(S): Drosophila melanogaster 
2014-05-12 | E-GEOD-53015 | biostudies-arrayexpress
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