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ProteomicsGraft versus host disease treatment with mesenchymal stem cells
graft versus host disease organoids were co-cultured with mesenchymal stem cells
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD034822 | Pride
Msc Proteomics Mass spectrometry Gvhd 
Proteomicsamyotrophic lateral sclerosis proteomic signature and treatment with mesenchymal stem cell-derived extracellular vesicles
identifying the proteomic signature of ALS and how this is changed after treatment with MSC-EVs
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD034824 | Pride
Proteomics Mesenchymal stem cells Extracellular vesicles Amyotrophic lateral sclerosis 
ProteomicsQuantitative proteomic alterations of human iPSC-based neuronal development indicate early onset of Rett syndrome.
Rett syndrome (RTT) is a progressive neurodevelopmental disease often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanisms by which impaired MeCP2 induces the pathological abnormalities in the brain is not understood. To understand the molecular mech...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013327 | Pride
Rett syndrome  ipsc  neuron differentiation  quantitative mass spectrometry  tmt-10plex 
ProteomicsSpinal Muscular Atrophy Patient iPSC-derived Motor Neurons Display Altered Proteins at Early Stages of Differentiation
Spinal muscular atrophy (SMA) is characterized by low levels of survival motor neuron (SMN) protein and loss of motor neurons (MN); however, the underlying mechanism that links SMN deficiency to selective motor neuronal dysfunction is still largely unknown. We present here, for the first time, a com...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD015115 | Pride
Spinal muscular atrophy (sma)  ipsc  neuron differentiation  quantitative mass spectrometry  tmt-10plex 
UnknownShared and distinct changes in the molecular cargo of extracellular vesicles in different neurodegenerative diseases.
Not available
S-EPMC11615177 | biostudies-literature
UnknownQuantitative proteomic analysis of Rett iPSC-derived neuronal progenitors.
Not available
S-EPMC7251722 | biostudies-literature
UnknownDeciphering the Proteome Dynamics during Development of Neurons Derived from Induced Pluripotent Stem Cells.
Not available
S-EPMC7281779 | biostudies-literature
UnknownSpinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Display Altered Proteomes at Early Stages of Differentiation.
Not available
S-EPMC8717385 | biostudies-literature
UnknownMesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model.
Not available
S-EPMC10210425 | biostudies-literature
UnknownATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes.
Not available
S-EPMC11362472 | biostudies-literature
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