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MetabolomicsPathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
UnknownActivation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells.
Not available
S-EPMC3665688 | biostudies-literature
UnknownMarker discovery and associations with β-carotene content in Indian dairy cattle and buffalo breeds.
Not available
S-EPMC7753891 | biostudies-literature
UnknownTrends and Drivers of Change of Pastoral Beef Production Systems in a Mediterranean-Temperate Climate Zone of Chile.
Not available
S-EPMC6941165 | biostudies-literature
UnknownEvaluating the effectiveness of care coordination interventions designed and implemented through a participatory action research process: Lessons learned from a quasi-experimental study in public healthcare networks in Latin America.
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S-EPMC8754346 | biostudies-literature
UnknownCan care coordination across levels be improved through the implementation of participatory action research interventions? Outcomes and conditions for sustaining changes in five Latin American countries.
Not available
S-EPMC7552474 | biostudies-literature
UnknownUnderstanding the factors influencing the implementation of participatory interventions to improve care coordination. An analytical framework based on an evaluation in Latin America.
Not available
S-EPMC7553758 | biostudies-literature
UnknownThe Expression Profiles of lncRNAs Are Associated with Neoadjuvant Chemotherapy Resistance in Locally Advanced, Luminal B-Type Breast Cancer.
Not available
S-EPMC11311431 | biostudies-literature
UnknownUnderstanding communication breakdown in the outpatient referral process in Latin America: a cross-sectional study on the use of clinical correspondence in public healthcare networks of six countries.
Not available
S-EPMC5894081 | biostudies-literature
MetabolomicsGNPS - KendrickMassFilter_EvaluationDataset_PUBLIC
Data set used in the evaluation of the Kendrick Mass Filter - a computational method of removing oligomer ions in mass spectral data.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081544 | GNPS
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