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MetabolomicsUtilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis
Characterizing the metabolic changes pertaining to hepatocellular carcinoma (HCC) in patients with liver cirrhosis is believed to contribute towards early detection, treatment, and understanding of the molecular mechanisms of HCC. In this study, we compare metabolite levels in sera of 78 HCC cases w...
MTBLS17 | MetaboLights
ProteomicsGlycoproteome Profiling of Human Serum for Hepatocellular Carcinoma Biomarker Discovery
Hepatocellular carcinoma (HCC) typically develops on a cirrhotic background, where conventional serum biomarkers such as alpha-fetoprotein (AFP) provide inconsistent performance. We implemented an integrated serum intact glycoproteomics strategy that profiles N-linked and O-linked glycopeptides in p...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD075370 | Pride
Nano-lc-ms/ms Liver cancer Glycoproteomics Human serum Biomarker 
MetabolomicsGC-MS Based Plasma Metabolomics for Identification of Candidate Biomarkers for Hepatocellular Carcinoma in Egyptian Cohort
This study evaluates changes in metabolite levels in hepatocellular carcinoma (HCC) cases vs. patients with liver cirrhosis by analysis of human blood plasma using gas chromatography coupled with mass spectrometry (GC-MS). Untargeted metabolomic analysis of plasma samples from participants recruited...
2015-08-13 | MTBLS105 | MetaboLights
MetabolomicsLC−MS Based Serum Metabolomics for Identification of Hepatocellular Carcinoma Biomarkers in Egyptian Cohort
Although hepatocellular carcinoma (HCC) has been subjected to continuous investigation and its symptoms are well-known, early stage diagnosis of this disease remains difficult and the survival rate after diagnosis is typically very low (3−5%). Early and accurate detection of metabolic changes in the...
2013-06-30 | MTBLS19 | MetaboLights
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