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TranscriptomicsAdvancing Trypanosoma brucei genome annotation through ribosome profiling and spliced leader mapping
Since the initial publication of the trypanosomatid genomes, curation has been ongoing. Here we apply the technique of ribosome profiling to Trypanosoma brucei, identifying 223 new coding regions by virtue of ribosome occupancy in the corresponding transcripts. A small number of these putative genes...
ORGANISM(S): Trypanosoma brucei 
2015-12-22 | E-GEOD-72463 | biostudies-arrayexpress
UnknownA roadmap to define and select aquatic biological traits at different scales of analysis.
Not available
S-EPMC10746726 | biostudies-literature
TranscriptomicsExpression profiling data from mid-log phase cultures of wild type Vibrio campbellii BAA-1116
Small RNA and regulatory RNA discovery has been based on (i) computational predictions mainly in intergenic regions, (ii) microarray experiments, (iii) shotgun cloning of cDNA libraries, (iv) classical cloning of abundant small RNAs after size fractionation in polyacrylamide gels and (v) copurificat...
ORGANISM(S): Vibrio harveyi ATCC BAA-1116 
2010-06-01 | E-GEOD-20960 | biostudies-arrayexpress
UnknownImpaired Thymic Output Can Be Related to the Low Immune Reconstitution and T Cell Repertoire Disturbances in Relapsing Visceral Leishmaniasis Associated HIV/AIDS Patients.
Not available
S-EPMC7251171 | biostudies-literature
TranscriptomicsMicroarray of MyT1 Gain-of-Function in NS5
Here we performed a microarray experiment on samples of adherent cultures of mouse neural stem cells (NS5 cell line) expressing an inducible version of the transcription factor MyT1 (MyT1-V5 TetON) under normal growth conditions and after 4 hours of treatment by doxycyline. This resulted in the gene...
ORGANISM(S): Mus musculus 
2016-09-09 | E-MTAB-4335 | biostudies-arrayexpress
MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
TranscriptomicsStage-specific regulation of translation revealed by ribosome profiling of Trypanosoma brucei
Trypanosoma brucei subspecies infect humans and animals in sub-Saharan Africa. This early diverging eukaryote shows many novel features in basic biological processes, including the use of polycistronic transcription to generate all protein-coding mRNAs. Therefore we hypothesized that translational...
ORGANISM(S): Trypanosoma brucei 
2014-05-24 | E-GEOD-57336 | biostudies-arrayexpress
UnknownImmune response and innervation signatures in aseptic hip implant loosening.
Not available
S-EPMC4937545 | biostudies-literature
UnknownAnti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
Not available
S-EPMC11251720 | biostudies-literature
UnknownClinical efficacy and safety of a light mask for prevention of dark adaptation in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial.
Not available
S-EPMC5908782 | biostudies-literature
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